Hormonal-metabolic changes in blood serum of rats in acute period after general controlled hyperthermia as a manifestation of hypermetabolism syndrome

Abstract

Hormonal-metabolic profile of blood serum of rats in 5 hours, on the first and third day after hyperthermia in water medium at the temperature of 45 °С till rectal temperature rose to 43.5 °С was studied. Hypercorticosteronaemia, hyperinsulinemia, hypoglycemia, hypocholesterolemia, hypotriglyceridaemia, hyperproteinemia and increase of protein metabolites level were revealed which was the evidence of hypermetabolism syndrome development during acute period after controlled hyperthermia.