2009
DOI: 10.1080/15532730903383757
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Hormone Therapy in Adults: Suggested Revisions to the Sixth Version of theStandards of Care

Abstract: Often viewed as the definitive professional document on transgender care, the current Standards of Care for Gender Identity Disorders-Sixth Version provides a general overview of the risks and effects of adult hormone therapy, but at present offers limited guidance for the medical provider as to how best to execute this critical intervention. Newer versions need to present a comprehensive approach to transgender hormone therapy, including preventive health care, by incorporating the following key elements: the… Show more

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Cited by 30 publications
(39 citation statements)
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References 192 publications
(244 reference statements)
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“…23,24 PCOS has been shown to increase the risk for hypertension in non-transgender women; thus, transgender men should be screened for symptoms of PCOS before initiating hormones. 2…”
Section: Transgender Menmentioning
confidence: 99%
See 3 more Smart Citations
“…23,24 PCOS has been shown to increase the risk for hypertension in non-transgender women; thus, transgender men should be screened for symptoms of PCOS before initiating hormones. 2…”
Section: Transgender Menmentioning
confidence: 99%
“…Estrogen therapy has been shown to minimally increase blood pressure; however, the clinical significance of this is unclear. 2,25 Spironolactone, with its antiandrogen properties, is often used as a part of a feminizing regimen for transgender women, and can be used to treat blood pressure to the defined target based on age.…”
Section: Transgender Womenmentioning
confidence: 99%
See 2 more Smart Citations
“…Apesar dos trabalhos acima contemplarem a população transgênero, a recomendação é classificada como fraca, uma vez que todos os estudos de morbibmortalidade específicos para essa população são retrospectivos.Por fim, o assunto de maior divergência entre os protocolos consiste nas recomendações para solicitação de exames no acompanhamento do hormonização. Um exemplo é a dosagem de transaminases.Enquanto o Guideline Trans -Toronto, embasado no aumento do risco de hiperprolactinemia e desenvolvimento de prolactinoma associado ao uso de estrogênio, indica controle de prolactina anual,39 o acompanhamento passaria a ser anual ou conforme a necessidade individual de cada paciente. 29 Tal decisão foi baseada no estudo prospectivo de mulheres transexuais em hormonização combinada de estradiol e espironolactona, que verificou que todas elas haviam alcançado níveis fisiológicos de estradiol em 6 meses e improvável benefício de monitoramento, uma vez que uma dosagem estável tenha sido atingida.…”
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