Horn Cancer in Cattle in Iraq

Zubaidy, A. J. Al

doi:10.1177/030098587601300608

Cited by 11 publications

(14 citation statements)

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“…8 Few cases were reported from Sumatra, 9 Brazil 10 and Iraq. 11 It is most commonly found in working bullocks (∼95% cases), sometimes in cows (∼5% cases) and rarely in bulls, buffaloes, sheep and goats. 12 -15 Gene expression profiling has not been studied in depth in HC yet due to, regional economy and limitations of available technologies.…”

Section: -6mentioning

confidence: 99%

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Comprehensive transcriptome profiling of squamous cell carcinoma of horn in Bos indicus

Koringa

Jakhesara

Bhatt

et al. 2013

Vet Comparative Oncology

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Squamous cell carcinoma (SCC) of horn is frequently observed in Bos indicus affecting 1% of cattle population and accounting 83.34% of total tumours found. The transcriptome profile of horn cancer (HC) tissue and the matched normal (HN) tissue were analysed by RNA-seq using Roche 454 sequencing. A total of 1 504 900 reads comprising of 612 MB data were used to identify differentially expressed genes using CLC Genomic Workbench. These include up-regulation of KRT6A, KRT6B, KRT6C, KRT14, SFN, KRT84, PI3, COL17A1, ANLN, SERPINB5 and down-regulation of BOLA, SCGB1A1, CXCL17, KRT19, BPIFB1, NR4A1 and TFF3 in HC, which are involved in regulation of gene transcription, cell proliferation, apoptosis, cell survival and metabolic pathways. The qPCR analysis of several targets suggested concordance of gene expression profile with RNA-seq analysis. The present findings would provide basis for further screening of genes and identification of markers for early diagnosis and therapeutic intervention of HC.

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Section: -6mentioning

confidence: 99%

“…The incidence of HC is more frequent in Kankrej breed than other zebu cattle, crossbred or non‐descript cattle . Few cases were reported from Sumatra, Brazil and Iraq . It is most commonly found in working bullocks (˜95% cases), sometimes in cows (˜5% cases) and rarely in bulls, buffaloes, sheep and goats …”

Section: Introductionmentioning

confidence: 99%

Comprehensive transcriptome profiling of squamous cell carcinoma of horn in Bos indicus

Koringa

Jakhesara

Bhatt

et al. 2013

Vet Comparative Oncology

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“…Essa neoplasia tem sido relatada, principalmente, na Índia com prevalência de 1% no rebanho bovino (Naik et al, 1969(Naik et al, , 1970, mas também é descrita na Sumatra (Burggraaf, 1935), Iraque (Zubaidy, 1976) e Brasil (Lemos, 1998). Acredita-se que a ocorrência dessa neoplasia no Brasil seja pouco frequente ou subnotificada devido ao sistema de produção, no qual a maioria dos animais são abatidos em idade precoce, reduzindo assim a incidência de neoplasias.…”

Section: Discussionunclassified

Carcinoma de células escamosas na base do chifre com metástase pulmonar em um bovino: relato de caso

Fernandes¹,

Araújo²,

Casagrande³

et al. 2017

Braz. J. Vet. Med.

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“…Bovine horn cancer (HC) a squamous cell carcinoma, was first reported by Hewlett (1905) from Maharashtra (India). The condition has since been recorded from most of the states in India (Kulkarni 1947;Nair and Sastry 1954;La11 1953; Kaul and Kalra 1973) and other countries such as Indonesia (Burgraf 1935), Brazil (Rezende and Neves 1976) and Iraq (Zubaidy 1976).…”

Section: Lntroductionmentioning

confidence: 99%

Tumour Associated Antigens in Bovine Horn Cancer

1982

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Tumour associated antigens in bovine horn cancer (HC) were demonstrated by immunodiffusion in agar gel and by immuno-fluorescence. Antiserums raised in rabbits against sonicated pooled horn cancer tissue extracts and absorbed with normal antigens, reacted only with HC extracts on agar gel diffusion. Preparations of normal antigen (skin, horn core epithelium, lymph node and liver) and extracts from other tumours (fibroma, fibrosarcoma and myxoma) did not show any reactivity against absorbed antiserum in this test. The absorbed antiserum showing specific reactivity to HC extracts in gel diffusion tests was conjugated to fluorescein isothiocyanate. Many different HC, normal cells and cells from other tumours were incubated with the conjugate and examined by fluorescent microscopy. HC cells showed specific beaded fluorescence on the surface whereas such fluorescence was not observed in normal cells or cells from other tumours.

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Horn Cancer in Cattle in Iraq

Cited by 11 publications

References 1 publication

Comprehensive transcriptome profiling of squamous cell carcinoma of horn in Bos indicus

Comprehensive transcriptome profiling of squamous cell carcinoma of horn in Bos indicus

Carcinoma de células escamosas na base do chifre com metástase pulmonar em um bovino: relato de caso

Tumour Associated Antigens in Bovine Horn Cancer

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