2014
DOI: 10.1007/s00347-014-3114-0
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Hornhautkollagenvernetzung mit Riboflavin und UVA-Licht bei Patienten mit progressivem Keratokonus

Abstract: The results of this study indicate that riboflavin and ultraviolet-A induced corneal CXL is a promising therapeutic option for progressing keratoconus to obtain long-term stabilization. There was a sustained improvement of all K-values and BCVA 10 years after treatment and CXL is minimally invasive and easy to handle. Side effects, such as endothelial damage did not occur.

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Cited by 29 publications
(14 citation statements)
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“…In the past 10 years, corneal cross-linking treatment has gained popularity. Adult patients who have undergone the procedure have less relapse [4], better functional and morphological results [55] and more sustainable effect over longer follow-up periods [56]. However, Soeters et al [54] did report more corneal flattening and more visual acuity improvement in children compared to adults after cross-linking, while Vinciguerra et al [57] reported better outcomes in adults ages 18–39.…”
Section: Difference Between Adult and Pediatric Keratoconusmentioning
confidence: 99%
“…In the past 10 years, corneal cross-linking treatment has gained popularity. Adult patients who have undergone the procedure have less relapse [4], better functional and morphological results [55] and more sustainable effect over longer follow-up periods [56]. However, Soeters et al [54] did report more corneal flattening and more visual acuity improvement in children compared to adults after cross-linking, while Vinciguerra et al [57] reported better outcomes in adults ages 18–39.…”
Section: Difference Between Adult and Pediatric Keratoconusmentioning
confidence: 99%
“…В последние годы для повышения биомеханической устойчивости склеры при миопии предложено использовать кросслинкинг склерального коллагена, индуцированный ультрафиолетовым облучением диапазона А (УФA) в сочетании с обработкой рибофлавином, являющимся инициатором фотополимеризации коллагена [6,7]. Этот подход показал высокую клиническую эффективность при лечении прогрессирующих эктазий другой соединительнотканной оболочки глаза -роговицы, в частности для лечения кератоконуса [4,8,9]. Однако для достижения склероукрепляющего эффекта необходимо обеспечить прямой доступ излучения к склере в экваториальной области и в области заднего полюса глаза.…”
Section: Experimental Realization Of Minimally Invasive Techniques Ofunclassified
“…Der Keratoconus ist eine degenerative Erkrankung der Hornhaut (HH), welche mit einer zentralen oder parazentralen Hornhautverdünnung, einer apikalen Protrusion der Hornhaut und einem irregulären Astigmatismus einhergeht und zu einer Sehverschlechterung führt [1]. Eine adäquate Erstbeschreibung des KC bei deutlicher Unterscheidung von anderen ektatischen HH-Erkrankungen erfolgte durch Nottingham 1854 [2].…”
Section: Definitionunclassified