Horseshoe lamination mixer (HLM) sets new standards in the production of monodisperse lipid nanoparticles

Abstract

Microfluidic mixers promise unique conditions for the controlled and continuous preparation of nanoparticles by antisolvent precipitation. Nanoparticles may enable encapsulation of drug or mRNA molecules in the form of carrier...

A techno-economic approach to guide the selection of flow recyclable ionic liquids for nanoparticle synthesis

“…The convective mixing can also be enhanced by the “widening” and “narrowing” effects of the wavy pattern on the liquid–liquid biphasic flow. 37 After extraction, the slug flow entered the separation section where a hydrophobic PTFE membrane selectively allowed the IL phase to permeate and be collected. The acidified aqueous stream carrying the impurities was retained in the upper channel.…”

Recent Advances in Multi‐Photon 3D Laser Printing: Active Materials and Applications

“…In 2019, Oellers et al prepared a fluidic micromixer by printing in a predefined channel. [168] In 2021 and 2022, multi-photon 3D laser printing of fluidic mixers and occurring flow dynamics were further investigated by Erfle et al [169,170] Printing inside microfluidic channels was also employed for manipulating and trapping micrometersized particles. [164,[171][172][173][174] It is noteworthy that multi-photon 3D laser printing was so far mainly used for printing solid barriers without the possibility of actively changing their shape.…”

Simple distance-based thread analytical device integrated with ion imprinted polymer for Zn2+ quantification in human urine samples

“…Recently, microfluidic thread-based analytical devices (µTADs) have gained more attention due to their simplicity, cost-effectiveness, rapid response, and ease of operation. [33][34][35][36][37] Since they allow the fluid to flow on the hydrophilic channel by capillary force, there is no need for an external microfluidic pump, saving cost and reducing overall complexity. Of all the readout methods for point-of-care (POC) testing, distancebased visual measurement offers a simpler approach without the need for instrumentation.…”