Hospital-based surveillance of influenza A(H1N1)pdm09 virus in Saudi Arabia, 2010-2016

Abdullahi, Osman; Mohammed, Mutaz; Hakawi, Ahmed; Aljifri, Alanoud; Abdalla, Mohamed M.; Eltigani, Sara; Mujib, Sahibzada Azhar; Assiri, Abdullah

doi:10.5144/0256-4947.2020.1

Cited by 8 publications

(9 citation statements)

References 14 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“… 20 In a recent study performed in KSA and based on the information obtained from the influenza A (H1N1) surveillance project, which was carried out from 2010-2016, a seasonal trend was observed, with a fatality rate of approximately 3.6%. 21 When examining influenza B, approximately 38.6% of our sample population were positive for influenza B IgG antibody. A similar percentage was reported by a study conducted in Riyadh, KSA in 2016, with a reported prevalence of 35% for influenza B IgG-positive individuals.…”

Section: Discussionmentioning

confidence: 88%

Natural immunity to influenza A and B among Saudi blood donors in Al Madinah Al Munawarah, Saudi Arabia

Mahallawi

Ibrahim

Alahmadi

et al. 2020

SMJ

View full text Add to dashboard Cite

Objectives: To investigate the seroprevalence of influenza viruses (A and B) among blood donors in Kingdom of Saudi Arabia. Methods: The present investigation was conducted between April 2019 and July 2019. Participants were healthy adults recruited from the central blood bank Al Madinah Al Munawarah, Kingdom of Saudi Arabia. Immunoglobulin G (IgG) levels against influenza A and B were measured in serum samples using ELISA. Original Article Results: The results showed that 29.2% of the sample had significant concentrations of influenza A IgG antibody, whereas 38.6% had significant concentrations of influenza B IgG antibody. A strong correlation was found between the levels of influenza A and influenza B antibodies (r=0.708, p<0.001). The number of individuals identified as negative for influenza A IgG antibody increased with age (p<0.01). In addition, no correlations were identified between influenza A IgG and influenza B IgG and body mass index (BMI), (p>0.05). Finally, linear regression analysis showed that the level of influenza A antibody can be predicted by age (p<0.05) and body mass index (BMI) (p<0.05). Conclusion: Approximately one-third of Saudi Arabian adults presented significant levels of influenza A and B antibodies in our study. Demographic factors, including age and BMI, might contribute to influenza A antibody levels.

show abstract

Section: Discussionmentioning

confidence: 88%

Natural immunity to influenza A and B among Saudi blood donors in Al Madinah Al Munawarah, Saudi Arabia

Mahallawi

Ibrahim

Alahmadi

et al. 2020

SMJ

View full text Add to dashboard Cite

show abstract

“…The Chinese version of PSS-14 scale adopted a 5-point scoring system (0=never, 1=almost never, 2=sometimes, 3=fairly often, 4=always). Of these, 7 items (1,2,3,8,11,12,14) belong to the negative dimension, and are scored from 0 to 4, while the other 7 items (items 4, 5, 6, 7, 9, 10, 13) belong to positive dimension, and are scored in reverse. PSS score is obtained by adding the 14 items together, the higher the score the greater the perceived stress.…”

Section: Perceived Stress Scale (Pss)mentioning

confidence: 99%

“…Background H1N1, SARS, Ebola, Zika and other infectious diseases frequently occur in recent years, posing serious threats to human health and development [1][2][3][4][5]. In December 2019, Corona Virus Disease 2019 (COVID-19) epidemic broke out in Wuhan, Hubei Province, and quickly spread to the whole country [6].…”

mentioning

confidence: 99%

Impact of COVID-19 on psychology of nurses working in the emergency and fever outpatient:A cross-sectional survey

Cui¹,

Jiang

Shi³

et al. 2020

Preprint

View full text Add to dashboard Cite

Background COVID-19 poses a great challenge to the global health system. The nurses of emergency and fever outpatient (EFO) act as gatekeepers to the health care system in the public health response to COVID-19 epidemic. This study examined the psychological impact of COVID-19 upon EFO nurses in Chinese hospitals. Methods In midmonth of February, 2020, convenience sampling was used to recruit EFO nurses from hospitals in Jiangsu Province. Data were obtained by self-administered online questionnaires, which consisted of a general questionnaire, the Self-Rating Anxiety Scale, Perceived Stress Scale-14 and Simplified Coping Style Questionnaire. A total of 481 questionnaires were returned and 453 valid questionnaires were recovered. Multiple linear regression was used to explore the influence of socio-psychological and working condition factors on anxiety, stress and stress coping tendency. Pearson correlation coefficients were calculated to assess the associations among anxiety, stress and coping tendency. Results Among the participants, 281(62.03%) had no anxiety symptoms, 154(34.00%) had mild anxiety, 16(3.53%) had moderate anxiety, and 2(0.44%) had severe anxiety. There were 146(32.23%) participants with scores greater than 25 in the PSS, indicating excessive stress. We found that 229(50.55%) participants were more likely to respond positively to stress, while 224(49.45%) were more likely to respond negatively. The models we used included gender, fear of infecting family members, regretting being a nurse, having children, confidence in fighting outbreak, rest time, professional attitudes, having attended infection prevention training, and number of night shifts; and they were all predictors of the mental health of EFO nurses. Pearson correlation showed a positive correlation of the anxiety with stress score (r=0.443, P<0.001), while the coping tendency score was found negatively correlated with anxiety (r=-0.268, P< 0.001) and stress (r=-0.503, P< 0.001). Conclusion COVID-19 has a certain psychosocial impact upon EFO nurses. Effective measures, such as strengthening protection training, adequate nurses for emergency and fever clinics, reducing night shifts, and timely updates of latest epidemic situation, should be taken. Moreover, greater attention should be paid to female EFO nurses and nurses with children.

show abstract

“…Surveillance system for detection of ILI cases and the causative agent has been established since 2009 [ 29 ]. The total outpatient numbers along with the number of ILI cases were reported on a weekly basis by one of the sentinel hospitals, and clinical samples were also collected from ILI patients.…”

Section: Methodsmentioning

confidence: 99%

Structural Mapping of Mutations in Spike, RdRp and Orf3a Genes of SARS-CoV-2 in Influenza Like Illness (ILI) Patients

Alosaimi

Naeem

Alghoribi

et al. 2021

Viruses

View full text Add to dashboard Cite

In December 2019, the emergence of SARS-CoV-2 virus in China led to a pandemic. Since both Influenza Like Illness (ILI) and COVID-19 case definitions overlap, we re-investigated the ILI cases using PCR for the presence of SARS-CoV-2 in 739 nasopharyngeal swabs collected from November 2019 to March 2020. SARS-CoV-2 RNA was found in 37 samples (5%) collected mostly during February 2020. It was followed by confirmation of evolutionary and spatial relationships using next generation sequencing (NGS). We observed that the overall incidence of ILI cases during 2019–2020 influenza season was considerably higher than previous years and was gradually replaced with SARS-CoV-2, which indicated a silent transmission among ambulatory patients. Sequencing of representative isolates confirmed independent introductions and silent transmission earlier than previously thought. Evolutionary and spatial analyses revealed clustering in the GH clade, characterized by three amino acid substitutions in spike gene (D614G), RdRp (P323L) and NS3 (Q57H). P323L causes conformational change near nsp8 binding site that might affect virus replication and transcription. In conclusion, assessment of the community transmission among patients with mild COVID-19 illness, particularly those without epidemiological link for acquiring the virus, is of utmost importance to guide policy makers to optimize public health interventions. The detection of SARS-CoV-2 in ILI cases shows the importance of ILI surveillance systems and warrants its further strengthening to mitigate the ongoing transmission of SARS-CoV-2. The effect of NS3 substitutions on oligomerization or membrane channel function (intra- and extracellular) needs functional validation.

show abstract

Hospital-based surveillance of influenza A(H1N1)pdm09 virus in Saudi Arabia, 2010-2016

Cited by 8 publications

References 14 publications

Natural immunity to influenza A and B among Saudi blood donors in Al Madinah Al Munawarah, Saudi Arabia

Natural immunity to influenza A and B among Saudi blood donors in Al Madinah Al Munawarah, Saudi Arabia

Impact of COVID-19 on psychology of nurses working in the emergency and fever outpatient:A cross-sectional survey

Structural Mapping of Mutations in Spike, RdRp and Orf3a Genes of SARS-CoV-2 in Influenza Like Illness (ILI) Patients

Contact Info

Product

Resources

About