Hospital epidemiologists’ and infection preventionists’ opinions regarding hospital-onset bacteremia and fungemia as a potential healthcare-associated infection metric

Dantes, Raymund; Abbo, Lilian M.; Anderson, Deverick J.; Hall, Lisa; Han, Jennifer H.; Harris, Anthony D.; Leekha, Surbhi; Milstone, Aaron M.; Morgan, Daniel J.; Safdar, Nasia; Schweizer, Marin L.; Sengupta, Shamik; Seo, Susan K.; Rock, Clare

doi:10.1017/ice.2019.40

Cited by 26 publications

(24 citation statements)

References 10 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…2 3 HOB rate is an objective measure and has been suggested as an indicator of changes in healthcare delivery. [4][5][6][7] We aimed to compare the incidence and mortality of HOB before and after the emergence of COVID-19.…”

Section: Introductionmentioning

confidence: 99%

“…One such outcome measure is hospital-onset bloodstream infection (HOB), which is closely related to central line-associated bloodstream infections, but also reflects bacteraemia secondary to other healthcare-associated infections 2 3. HOB rate is an objective measure and has been suggested as an indicator of changes in healthcare delivery 4–7. We aimed to compare the incidence and mortality of HOB before and after the emergence of COVID-19.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Impact of the COVID-19 pandemic on the incidence and mortality of hospital-onset bloodstream infection: a cohort study

et al. 2022

View full text Add to dashboard Cite

The COVID-19 pandemic burdens hospitals, but consequences for quality of care outcomes such as healthcare-associated infections are largely unknown. This cohort included all adult hospital episodes (n=186 945) at an academic centre between January 2018 and January 2021. Data were collected from the hospitals’ electronic health record data repository. Hospital-onset bloodstream infection (HOB) was defined as any positive blood culture obtained ≥48 hours after admission classified based on microbiological and hospital administrative data. Subgroup analyses were performed with exclusion of potential contaminant bacteria. The cohort was divided into three groups: controls (prepandemic period), non-COVID-19 (pandemic period) and COVID-19 (pandemic period) based on either PCR-confirmed SARS-CoV-2 infections from respiratory samples or International Classification of Diseases 10th Revision diagnoses U071 and U72 at discharge. Adjusted incidence rate ratios (aIRR) and risk of death in patients with HOB were compared between the prepandemic and pandemic periods using Poisson and logistic regression. The incidence of HOB was increased for the COVID-19 group compared with the prepandemic period (aIRR 3.34, 95% CI 2.97 to 3.75). In the non-COVID-19 group, the incidence was slightly increased compared with prepandemic levels (aIRR 1.20, 95% CI 1.08 to 1.32), but the difference decreased when excluding potential contaminant bacteria (aIRR 1.15, 95% CI 1.00 to 1.31, p=0.04). The risk of dying increased for both the COVID-19 group (adjusted odds ratio (aOR) 2.44, 95% CI 1.75 to 3.38) and the non-COVID-19 group (aOR 1.63, 95% CI 1.22 to 2.16) compared with the prepandemic controls. These findings were consistent also when excluding potential contaminants. In summary, we observed a higher incidence of HOB during the COVID-19 pandemic, and the mortality risk associated with HOB was greater, compared with the prepandemic period. Results call for specific attention to quality of care during the pandemic.

show abstract

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Impact of the COVID-19 pandemic on the incidence and mortality of hospital-onset bloodstream infection: a cohort study

et al. 2022

View full text Add to dashboard Cite

show abstract

“…Example 1 describes two surveillance definitions for bacteraemia and bloodstream infections that are amenable to fully AS. HOB is a concept currently under study in the United States [31,32,45]. The Danish Healthcare-Associated Infections Database (HAIBA) bacteraemia definition is included in the Danish AS network [39].…”

Section: Definitionsmentioning

confidence: 99%

PRAISE: providing a roadmap for automated infection surveillance in Europe

Mourik

Rooden

Abbas

et al. 2021

Clinical Microbiology and Infection

View full text Add to dashboard Cite

Introduction: Healthcare-associated infections (HAI) are among the most common adverse events of medical care. Surveillance of HAI is a key component of successful infection prevention programmes.Conventional surveillance e manual chart review e is resource intensive and limited by concerns regarding interrater reliability. This has led to the development and use of automated surveillance (AS). Many AS systems are the product of in-house development efforts and heterogeneous in their design and methods. With this roadmap, the PRAISE network aims to provide guidance on how to move AS from the research setting to large-scale implementation, and how to ensure the delivery of surveillance data that are uniform and useful for improvement of quality of care. Methods: The PRAISE network brings together 30 experts from ten European countries. This roadmap is based on the outcome of two workshops, teleconference meetings and review by an independent panel of international experts. Results: This roadmap focuses on the surveillance of HAI within networks of healthcare facilities for the purpose of comparison, prevention and quality improvement initiatives. The roadmap does the following: discusses the selection of surveillance targets, different organizational and methodologic approaches and their advantages, disadvantages and risks; defines key performance requirements of AS systems and suggestions for their design; provides guidance on successful implementation and maintenance; and discusses areas of future research and training requirements for the infection prevention and related disciplines. The roadmap is supported by accompanying documents regarding the governance and information technology aspects of implementing AS. Conclusions: Large-scale implementation of AS requires guidance and coordination within and across surveillance networks. Transitions to large-scale AS entail redevelopment of surveillance methods and their interpretation, intensive dialogue with stakeholders and the investment of considerable resources. This roadmap can be used to guide future steps towards implementation, including designing solutions for AS and practical guidance checklists.

show abstract

“…4 Many epidemiologists support reporting rates of HOB as a quality measure either in addition to or instead of CLABSI. 5 We investigated if IAC use is associated with increased risk of HOB.…”

mentioning

confidence: 99%

Intraarterial Catheter Use Is Associated With Increased Risk of Hospital Onset Bacteremia

Barros

Enfield

Kadl

2021

Chest

View full text Add to dashboard Cite

Hospital epidemiologists’ and infection preventionists’ opinions regarding hospital-onset bacteremia and fungemia as a potential healthcare-associated infection metric

Cited by 26 publications

References 10 publications

Impact of the COVID-19 pandemic on the incidence and mortality of hospital-onset bloodstream infection: a cohort study

Impact of the COVID-19 pandemic on the incidence and mortality of hospital-onset bloodstream infection: a cohort study

PRAISE: providing a roadmap for automated infection surveillance in Europe

Intraarterial Catheter Use Is Associated With Increased Risk of Hospital Onset Bacteremia

Contact Info

Product

Resources

About