Hospital Planning and design can have a significant impact on environmental health, and even seemingly minor mistakes or oversights can contribute to negative health outcomes for patients and hospital staff. This paper examines the impact of invisible, unnoticeable, and overlooked mistakes in hospital design on environmental health in Egypt, with a focus on identifying the risks associated with these mistakes and exploring strategies for mitigating negative outcomes. Through a review of the literature, this paper identifies several key environmental factors that can contribute to negative health outcomes in hospitals, including poor air quality, inadequate ventilation, noise pollution, infection, poor materials quality, inadequate lighting and any other factors could harm the hospital occupants. Additionally, this paper examines the impact of these factors on patient outcomes, including length of stay, recovery time, and overall health and well-being. Finally, this paper explores and studies these mistakes which are considered a frequent phenomenon in a large number of hospitals in Egypt to determine these environmental health risks. Overall, this paper highlights the importance of considering even the smallest details in hospital design, and offers recommendations for promoting healthy and safe hospital environments in Egypt.