Hospital, Maternal and Birth Factors Associated With Hepatitis B Vaccination at Birth

Massey, Joel; Nair, Anil K.; Dietz, Stephanie; Snaman, Deborah; Bixler, Danae

doi:10.1097/inf.0000000000001953

Cited by 9 publications

(9 citation statements)

References 10 publications

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“…To prevent the vertical transmission of HBV, vaccination and Antiviral therapy for the infected pregnant women is very crucial [8]. Hepatitis B vaccination should be also given for the infants who are infected with HBV [9].…”

Section: Introductionmentioning

confidence: 99%

Prevalence and associated factors of hepatitis B virus infection among pregnant women attending antenatal care at Agena health center, South Ethiopia, 2019: a cross sectional study

Workye¹,

Robele²,

Ayele³

et al. 2019

Preprint

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Background; Hepatitis B virus (HBV) is the world’s most common and highly contagious liver infection. Its transmission methods are: mother to child, via open wounds, sexual contact, blood transfusion and other blood contact related activities. Prevalence of HBV among pregnant women in Africa ranges from 3.67 - 16.5% and in Ethiopia 2.4 to 8.4%. Hepatitis B infection leads to high morbidity and mortality for mother as well as for their infants due to the vertical transmission. Hence assessing the prevalence and associated factors of Hepatitis B Virus infection is a priority. Methodology : An institution based cross sectional study was conducted with a total of 194 of pregnant women attending antenatal care at Agena health center from May 1-30/2019. Frequency analysis and Logistic regression test was used to determine the associated factors associated with Hepatitis B virus by using SPSS version 25. Results: The prevalence of HBV in Agena health center among pregnant women were 4.1% and it was associated with marital status, history of hospital admission and history of abortion. Conclusion : The prevalence of HBV in Agena health center among pregnant women was intermediate. Since routine screening and immunization of all pregnant women is mandatory. Key words : Hepatitis B infection, pregnant women, Agena health center

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Section: Introductionmentioning

confidence: 99%

Prevalence and associated factors of hepatitis B virus infection among pregnant women attending antenatal care at Agena health center, South Ethiopia, 2019: a cross sectional study

Workye¹,

Robele²,

Ayele³

et al. 2019

Preprint

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“…Several studies of influenza and neonatal hepatitis B vaccination used automatic ordering/built-in order sets 43 46 54 57 58 61 65 66. Massey et al found that admission orders were associated with increased neonatal hepatitis B vaccination and Connors et al found that uptake of hepatitis B vaccination in a hospital where it was on a standing order was 93%–96% versus 71%–77% where it was not 66…”

Section: Resultsmentioning

confidence: 99%

Interventions delivered in secondary or tertiary medical care settings to improve routine vaccination uptake in children and young people: a scoping review

et al. 2022

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ObjectiveTo identify and analyse the interventions delivered opportunistically in secondary or tertiary medical settings, focused on improving routine vaccination uptake in children and young people.DesignScoping review.Search strategyWe searched CINAHL, Web of Science, Medline, Embase and Cochrane Database of Systematic Reviews for studies in English published between 1989 and 2021 detailing interventions delivered in secondary or tertiary care that aimed to improve childhood vaccination coverage. Title, abstract and full-text screening were performed by two independent reviewers.ResultsAfter deduplication, the search returned 3456 titles. Following screening and discussion between reviewers, 53 studies were included in the review. Most papers were single-centre studies from high-income countries and varied considerably in terms of their study design, population, target vaccination, clinical setting and intervention delivered. To present and analyse the study findings, and to depict the complexity of vaccination interventions in hospital settings, findings were presented and described as a sequential pathway to opportunistic vaccination in secondary and tertiary care comprising the following stages: (1) identify patients eligible for vaccination; (2) take consent and offer immunisations; (3) order/prescribe vaccine; (4) dispense vaccine; (5) administer vaccine; (6) communicate with primary care; and (7) ongoing benefits of vaccination.ConclusionsMost published studies report improved vaccination coverage associated with opportunistic vaccination interventions in secondary and tertiary care. Children attending hospital appear to have lower baseline vaccination coverage and are likely to benefit from vaccination interventions in these settings. Checking immunisation status is challenging, however, and electronic immunisation registers are required to enable this to be done quickly and accurately in hospital settings. Further research is required in this area, particularly multicentre studies and cost-effectiveness analysis of interventions.

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“…Both higher maternal age and white race are associated with birth dose HepB vaccine nonreceipt. 11,12 Interventions that were associated with centerline shifts were (1) addressing parent, physician, and staff misperceptions around HepB vaccine and lack of knowledge regarding HBV, (2) standardizing the timing of HepB vaccination and using scripts when discussing HepB vaccine with parents, and (3) multidisciplinary consensus. Discussion at monthly meetings contributed to modification of interventions and facilitated collaboration between pediatrics and obstetrics.…”

Section: Discussionmentioning

confidence: 99%

“…Interventions that improve HepB vaccine birth dose rates include standing orders and the codification of a hospital birth dose policy. [11][12][13] Furthermore, enhancements in the vaccine ordering and delivery processes combined with staff education have resulted in improved vaccination rates for birth dose HepB vaccination as well as other vaccines administered in inpatient settings. [13][14][15][16] However, despite national and state recommendations, use of a standing order, and the presence of a hospital birth dose policy, our institutional MBU HepB vaccination birth dose rates were well below national and city averages.…”

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confidence: 99%

Improving Birth Dose Hepatitis B Vaccination Rates: A Quality Improvement Intervention

Bradshaw¹,

DiFrisco

Schweizer

et al. 2020

Hospital Pediatrics

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BACKGROUND: There are 43 000 new cases of hepatitis B virus infection and 1000 cases of perinatally acquired infection each year in the United States. National recommendations are to administer hepatitis B (HepB) vaccine to all stable newborns .2000 g within 24 hours of birth. Our primary objective was to increase institutional vaccination rates from a baseline of 52% to goal .85% before hospital discharge. METHODS:In February 2017, we instituted a multidisciplinary quality improvement project aimed at increasing HepB vaccination birth dose rates. Interventions included (1) standardizing the process of offering HepB vaccine via scripting and timing, (2) engaging and educating parents, and (3) educating physicians and nurses regarding the importance of HepB vaccination and strategies to discuss HepB vaccination with vaccine-hesitant parents. The main outcome measure was the percentage of newborns receiving HepB vaccination by discharge. The secondary outcome was the percentage of newborns receiving HepB vaccination by 12 hours of life per New York State Department of Health recommendation. Data were analyzed by using statistical process control P-charts.RESULTS: A total of 21 108 newborns were included between July 2015 and April 2019. In addition to several upward centerline shifts, implementation of interventions resulted in increased and sustained HepB vaccination rates by hospital discharge from a baseline of 52.4% to 72.5%. Rates by 12 hours of life increased from 21.5% to 42.5%. CONCLUSIONS:Multidisciplinary collaboration, scripting, and provider and staff education regarding the risks of hepatitis B virus, benefits of HepB vaccine, and strategies to discuss HepB vaccination with parents significantly increased vaccination rates. Further efforts to improve vaccination rates to within 12 hours are preferable.

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Hospital, Maternal and Birth Factors Associated With Hepatitis B Vaccination at Birth

Abstract: Hospitals using preprinted admission orders had higher frequencies of HepB birth dose receipt. Additional study is needed to identify HepB birth dose receipt barriers among infants with maternal illicit drug use, maternal age ≥35 years or deliveries during a weekend.

Cited by 9 publications

References 10 publications

Prevalence and associated factors of hepatitis B virus infection among pregnant women attending antenatal care at Agena health center, South Ethiopia, 2019: a cross sectional study

Prevalence and associated factors of hepatitis B virus infection among pregnant women attending antenatal care at Agena health center, South Ethiopia, 2019: a cross sectional study

Interventions delivered in secondary or tertiary medical care settings to improve routine vaccination uptake in children and young people: a scoping review

Improving Birth Dose Hepatitis B Vaccination Rates: A Quality Improvement Intervention

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