Hospitalizations and testing in gastroparesis

Dudekula, Anwar; O’Connell, Michael; Bielefeldt, Klaus

doi:10.1111/j.1440-1746.2011.06735.x

Cited by 49 publications

(71 citation statements)

References 31 publications

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“…However, the number of hospital discharges were higher among women in both years, consistent with the finding that women are more predisposed to develop this disorder. This increase in rate of hospitalization for women could be because of increased health care seeking behavior by women, as reported previously[22]. Also, functional symptoms and delayed gastric emptying is more commonly seen in women than men[22-25].…”

Section: Discussionmentioning

confidence: 57%

“…Though there was a decrease in average length of stay, it was found that the cost of each hospitalization has increased considerably, after adjusting for inflation. Nonspecific symptoms at presentation leading to increased utilization of diagnostic modalities are one of the possible reasons for increasing the overall cost of hospitalizations[22]. Advances in diagnostic as well as therapeutic approaches such as GES implantations and surgical interventions also add to overall treatment expenditure.…”

Section: Discussionmentioning

confidence: 99%

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Healthcare utilization and costs associated with gastroparesis

Wadhwa¹,

Mehta²,

Jobanputra³

et al. 2017

WJG

111

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AIMTo use a national database of United States hospitals to evaluate the incidence and costs of hospital admissions associated with gastroparesis.METHODSWe analyzed the National Inpatient Sample Database (NIS) for all patients in whom gastroparesis (ICD-9 code: 536.3) was the principal discharge diagnosis during the period, 1997-2013. The NIS is the largest publicly available all-payer inpatient care database in the United States. It contains data from approximately eight million hospital stays each year. The statistical significance of the difference in the number of hospital discharges, length of stay and hospital costs over the study period was determined by regression analysis.RESULTSIn 1997, there were 3978 admissions with a principal discharge diagnosis of gastroparesis as compared to 16460 in 2013 (P < 0.01). The mean length of stay for gastroparesis decreased by 20 % between 1997 and 2013 from 6.4 d to 5.1 d (P < 0.001). However, during this period the mean hospital charges increased significantly by 159 % from $13350 (after inflation adjustment) per patient in 1997 to $34585 per patient in 2013 (P < 0.001). The aggregate charges (i.e., “national bill”) for gastroparesis increased exponentially by 1026 % from $50456642 ± 4662620 in 1997 to $568417666 ± 22374060 in 2013 (P < 0.001). The percentage of national bill for gastroparesis discharges (national bill for gastroparesis/total national bill) has also increased over the last 16 years (0.0013% in 1997 vs 0.004% in 2013). During the study period, women had a higher frequency of gastroparesis discharges when compared to men (1.39/10000 vs 0.9/10000 in 1997 and 5.8/10000 vs 3/10000 in 2013). There was a 6-fold increase in the discharge diagnosis of gastroparesis amongst type 1 DM and 3.7-fold increase amongst type 2 DM patients over the study period (P < 0.001).CONCLUSIONThe number of inpatient admissions for gastroparesis and associated costs have increased significantly over the last 16 years. Inpatient costs associated with gastroparesis contribute significantly to the national healthcare bill. Further research on cost-effective evaluation and management of gastroparesis is required.

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Section: Discussionmentioning

confidence: 57%

Section: Discussionmentioning

confidence: 99%

Healthcare utilization and costs associated with gastroparesis

Wadhwa¹,

Mehta²,

Jobanputra³

et al. 2017

WJG

111

View full text Add to dashboard Cite

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“…Dyspepsia is defined by the presence of symptoms believed to originate from the gastroduodenal region 29. FD is defined when these symptoms cannot be explained by any organic, systemic or metabolic diseases.…”

Section: Problem Areasmentioning

confidence: 99%

Gastroparesis: separate entity or just a part of dyspepsia?

Stanghellini

Tack

2014

Gut

137

159

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Gastroparesis is defined by the presence of delayed gastric emptying (GE) in the absence of mechanical obstruction. Symptoms that have been attributed to gastroparesis include postprandial fullness, early satiation nausea and vomiting. Gastroprokinetic drugs are the preferred treatment option. A number of problems with the concept of gastroparesis have been identified recently. Major overlap exists with the symptom complex of the functional dyspepsia subtype of postprandial distress syndrome. The distinguishing feature of gastroparesis is delayed GE, but the correlation between delayed emptying and symptom pattern or severity in gastroparesis is modest and the stability of delayed emptying over time is poor. Other pathophysiological mechanisms such as hypersensitivity or impaired accommodation may also underlie symptoms in patients with gastroparesis. Moreover, symptomatic response to prokinetic therapy is variable and cannot be predicted based on the degree of enhancing GE. A number of approaches have been proposed to increase clinical usefulness of a diagnosis of gastroparesis, including a higher threshold of abnormal emptying and selection of patients with a specific symptom pattern more likely to be associated with delayed emptying.

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“…Thus, alternative interventions have been actively explored. Gastroparesis and severe dyspepsia represent two conditions that affect quality of life, are associated with high medical costs [1, 2], and are often refractory to dietary and pharmacological interventions.…”

Section: Introductionmentioning

confidence: 99%

A Gastrointestinal Electrical Stimulation System Based on Transcutaneous Power Transmission Technology

Zhu

Wang

Yan

et al. 2014

Gastroenterology Research and Practice

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Electrical stimulation has been suggested as a possible treatment for various functional gastrointestinal disorders (FGID). This paper presents a transcutaneous power supplied implantable electrical stimulation system. This technology solves the problem of supplying extended power to an implanted electrical stimulator. After implantation, the stimulation parameters can be reprogrammed by the external controller and then transmitted to the implanted stimulator. This would enable parametric studies to investigate the efficacy of various stimulation parameters in promoting gastrointestinal contractions. A pressure detector in the internal stimulator can provide real-time feedback about variations in the gastrointestinal tract. An optimal stimulation protocol leading to cecal contractions has been proposed: stimulation bursts of 3 ms pulse width, 10 V amplitude, 40 Hz frequency, and 20 s duration. The animal experiment demonstrated the functionality of the system and validated the effects of different stimulation parameters on cecal contractions.

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Hospitalizations and testing in gastroparesis

Cited by 49 publications

References 31 publications

Healthcare utilization and costs associated with gastroparesis

Healthcare utilization and costs associated with gastroparesis

Gastroparesis: separate entity or just a part of dyspepsia?

A Gastrointestinal Electrical Stimulation System Based on Transcutaneous Power Transmission Technology

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