Hospitalizations for Diarrhea in Quebec Children from 1985 to 1998: Estimates of Rotavirus‐Associated Diarrhea

Abstract

The present article shows the importance of diarrhea hospitalizations among children and the alternating peak-year periodicity.

Burden of Rotavirus Disease: A Population‐Based Study in Eastern Townships, Quebec

“…Currently, in Canada, the number of rotavirus-associated AGE-related hospitalizations have been estimated to be between 19 and 45 cases per 10,000 children <5 years of age (4)(5)(6)(7)(8)(9)(10)(11)(12)(13)(14)(15). Core studies have focused only on standard hospitalizations in pediatric units; no data have been published on short-stay unit (SSU) hospitalizations, an emerging alternative for AGE management in the past 10 years.…”

“…To evaluate the proportion of AGE attributable to rotaviruses, the present study used two previously validated methods: the winter residual estimation (WRE) (16,17), which is calculated on the basis of the difference between winter and summer AGE cases, and the Brandt method (18), which involves the application of proportions of confirmed rotavirus-associated AGE as obtained during an eight-year surveillance study. According to the literature, these methods yield similar results (15,19,20). For the indirect residual method, winter months were defined as the months of December through May.…”

Rotavirus Vaccination: Cost‐Effectiveness and Impact on Child Mortality in Developing Countries

“…We calculated mean outpatient and hospital unit costs for each region by taking a population-weighted mean of country-specific cost estimates. We estimated the mean length of hospital stay as 4 days [6,[16][17][18][19][20][21][22][23][24][25][26][27][28][29][30][31][32][33][34][35], and diagnostic and medication costs were estimated as a proportion of the per visit and per diem costs [73,74]. Cost estimates were converted from year 2000 international dollars to 2007 US dollars with use of the Consumer Price Index [75], purchasing power parity, and official exchange rates [76].…”

Literature Review on Rotavirus: Disease and Vaccine Characteristics

“…(48) (46) Hospital (n=18) Ford-Jones, 2000 (45) ER (n=9) Ford-Jones, 2000 (47) Pediatric practices (n=4) Ford-Jones, 2000 (47) Day care centres (n=19) Ford-Jones, 2000 (47) Physician offices and pediatric clinics (n=59) Senecal (44) In a comprehensive review of diarrhea-associated hospitalizations in Quebec in the 13-year period between 1985 and 1998, there were 63,827 hospitalizations of children under the age of 5 years. (49) The number of cases attributable to RV in Quebec is estimated to be 1,506 per year using the method of Jin, (50) and 1,817 per year using the 37% RV causality rate in the Toronto area study. (45) Adenovirus, torovirus, norovirus, astrovirus and calicivirus also cause hospitalized gastroenteritis cases, though far less commonly (Table 3).…”