Hospitalizations of Older Patients with Human Immunodeficiency Virus in the United States

Tadros, Allison; Shaver, Erica; Davis, Stephen M.; Davidov, Danielle M.

doi:10.1016/j.jemermed.2012.02.028

Cited by 4 publications

(8 citation statements)

References 7 publications

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“…This finding is consistent with pneumonia being the most common primary diagnosis in patients with HIV infection in the United States between 2000 and 2006. 44 It is interesting to note that the primary diagnoses (non-ADI and ADI) of this study’s patient admissions were distributed among 15 of the 18 ICD -9- CM -based classification groups, 34 reflecting the “clinical” diversity of the patient population.…”

Section: Discussionmentioning

confidence: 92%

The Acute Care Physical Therapy HIV/AIDS Patient Population

Kinirons

2013

J Int Assoc Provid AIDS Care

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This study was based on an analysis of an existing database compiled from 475 medical records of people living with HIV/AIDS admitted to an acute-care hospital in New York City in 2004. The characteristics of patients with HIV infection that received physical therapy were determined. Differences between patients with HIV infection that did and did not receive physical therapy, as well as predictors of receipt of physical therapy, were identified. The physical therapy subgroup (n = 69) had a mean age of 48.3 years, consisted of more men than women, and was predominately black, with public health insurance. Admissions were commonly due to non-AIDS-defining illness as the primary diagnoses, accompanied by several comorbidities. Admissions often presented with functional deficits, incurred a prolonged length of stay, and required assistance at discharge. Differences existed between the physical therapy subgroup and the non-physical therapy subgroup (n = 406). Predictors of receipt of physical therapy were functional status on admission and length of stay.

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Section: Discussionmentioning

confidence: 92%

The Acute Care Physical Therapy HIV/AIDS Patient Population

Kinirons

2013

J Int Assoc Provid AIDS Care

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“…Many recent studies suggest that PWH aged > 50 are more likely to have HANA comorbidities, 7,27,28,46 and HANA-associated hospital stays. [29][30][31][32] Long-term use of antiretroviral drugs, sustained HIV-induced chronic immune activation and inflammation are referred to as factors associated with accelerated or early ageing, which may lead to an elevated risk of developing multiple comorbidities as PWH age. [6][7][8][9][47][48][49] Smit et al predict that, in the Netherlands, 84% of PWH will have at least one chronic condition, and 28% of PWH will have three or more chronic conditions by 2030.…”

Section: Discussionmentioning

confidence: 99%

“…23 Moreover, factors related to the ageing of PWH, including increased comorbidity and frailty, may increase the likelihood of hospitalization and length of hospital stay among the older population. [26][27][28][29][30][31][32] Declining trends in the mean age difference between the HSWH and HSWOH and an increasing proportion of Medicare beneficiaries among HSWH highlight the impact of ageing PWH on US inpatient departments. Studies using NIS data found increasing trends of Medicare as the primary payer for HSWH 12,24 and for hospital stays with other diagnoses.…”

Section: Discussionmentioning

confidence: 99%

Ageing with HIV in the United States: Changing trends in inpatient hospital stays and comorbidities, 2003–2015

et al. 2022

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Introduction As people with HIV (PWH) age, they experience prolonged exposure to HIV and antiretroviral therapy, increased risks of developing age‐related HIV‐associated non‐AIDS (HANA) comorbidities and higher rates of hospitalization. Few studies have explored the ageing of PWH and its impact on hospital stays in the US. This study examined trends, characteristics and comorbidities associated with hospital stays with HIV (HSWH) as compared with hospital stays without HIV (HSWOH). Methods Thirteen years of pooled National Inpatient Sample (NIS) data from 2003 through 2015 were analysed to describe yearly trends. Trends were evaluated for eight major HANA conditions (cardiovascular disease, cancer, diabetes, liver disease, bone loss, kidney disease, pulmonary disease and neurological disease) across four age groups (18–34, 35–49, 50–64, 65+ years). Results Although overall rates of hospitalization reduced across all age groups, the proportion of HIV‐related hospitalization increased among older Americans. The average number of chronic conditions was higher for HSWH among all age groups and disproportionately increased for older PWH. Although age‐adjusted rates of cardiovascular disease, cancer, bone loss and pulmonary disease were lower for HSWH relative to HSWOH, rates increased disproportionately over the study period. The prevalence of all major HANA conditions except cancer and diabetes increased among the elderly (65+), and the prevalence of cardiovascular disease, cancer, bone loss, kidney disease and pulmonary disease also increased among patients aged 50–64 years. Conclusions Higher rates of hospitalizations and HANA comorbidities were observed among older HIV patients. The ageing of PWH suggests increased future hospital resource utilization for HSWH. Appropriate training of healthcare providers is essential to managing increased comorbidity burdens of older PWH during hospital stays in the US.

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“…Since the introduction of HAART, older and middle-aged HIV-infected adults have represented a growing population, and the onset of age-related illnesses has contributed to the growing prevalence of co-morbidities (Tadros, Shaver, Davis, & Davidov, 2012). In a study of HIV-infected adults that spanned the years 2000 to 2006, hospitalization rates for persons ≥ 50 years of age were 47.5% compared with 19.6% for persons ≤49 years of age (Metallidis et al, 2013).…”

Section: Morbidity and Mortality In The Pre-haart And Haart Erasmentioning

confidence: 99%

“…In a study of HIV-infected adults that spanned the years 2000 to 2006, hospitalization rates for persons ≥ 50 years of age were 47.5% compared with 19.6% for persons ≤49 years of age (Metallidis et al, 2013). Compared with uninfected persons, HIV-infected persons are more likely to have renal failure, hepatitis B and C, cardiovascular disease, hypertension, and bone fractures (Berry, Fleishman, Moore, Gebo, & HIV Research Network, 2012;Betz et al, 2005;Crum-Cianflone et al, 2010;Davalos, Hlaing, Kim, & Rosa, 2010;Falster et al, 2010;Guaraldi et al, 2011;Oramasionwu et al, 2009;Tadros et al, 2012). Typically, these illnesses are seen in older adults; however, in HIV-infected persons, these illnesses have an early onset, suggesting that HIV infection induces premature aging (Caron, Auclair, Vissian, Vigouroux, & Capeau, 2008;Debarle, Lagsthu, Boccara, Vigouroux, & Capeau, 2010;Deeks, 2011;Guaraldi et al, 2009).…”

Section: Morbidity and Mortality In The Pre-haart And Haart Erasmentioning

confidence: 99%

Factors Associated With Hospitalizations Among HIV-Infected Adults in the United States

et al. 2014

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Although improving health outcomes in human immunodeficiency virus (HIV)-infected persons has been identified as a national priority, little is known about the factors associated with hospitalizations of HIV-infected persons in the highly active antiretroviral therapy (HAART) era. Since the introduction of HAART in 1996, there has been a dramatic increase in the life expectancy of HIV-infected persons. However, aging and the long term use of HIV medications have led to an increased incidence of chronic, non-HIV-related illnesses. To improve patient outcomes, the factors that contribute to co-morbidities in HIV-infected persons need to be identified. As a first step, we will summarize the current literature on causes and contributing factors of hospitalizations in adults infected with HIV in the HAART era.

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Hospitalizations of Older Patients with Human Immunodeficiency Virus in the United States

Cited by 4 publications

References 7 publications

The Acute Care Physical Therapy HIV/AIDS Patient Population

The Acute Care Physical Therapy HIV/AIDS Patient Population

Ageing with HIV in the United States: Changing trends in inpatient hospital stays and comorbidities, 2003–2015

Factors Associated With Hospitalizations Among HIV-Infected Adults in the United States

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