Host Cell and Antibody Response towards &lt;i&gt;Pasteurella Multocida&lt;/i&gt; B2 Infection-A General Review

Chung, Eric Lim Teik; Abdullah, Faez Firdaus Jesse; Abba, Yusuf; Marza, Ali Dhiaa; Ibrahim, Hayder Hamzah; Zamri‐Saad, Mohd; Wahid, H.; Saharee, Abdul Aziz; Lila, Mohd Azmi Mohd

doi:10.3844/ajavsp.2015.156.161

Cited by 4 publications

(1 citation statement)

References 26 publications

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“…Pasteurellosis is a serious and highly contagious bacterial infection affecting cattle and causing symptoms such as pneumonia, fever, and septicemia. The disease is caused by the gram-negative bacteria P. multocida found in the nasal passages and gastrointestinal tract of healthy animals (Chung et al 2015).…”

Section: Introductionmentioning

confidence: 99%

Development of Veterinary and Sanitary Measures for the Prevention of Pasteurellosis Infection in Cattle: The Case of the Republic of Kazakhstan

2023

Int J Vet Sci

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Cattle pasteurellosis is a dangerous infectious disease that leads to the death of farm animals just within a few days. This disease also spreads to many other wild animals, birds, and humans. Therefore, it is extremely important to understand the main manifestations of this disease and take timely measures to eliminate it. The study aimed to determine the strategy of veterinary and sanitary measures in the Republic of Kazakhstan for the prevention of pasteurellosis infection, based on the determination of zones by cattle pasteurellosis spread and the compilation of visualization maps using the results of the 2013-2021 monitoring. A clinical examination of cattle was carried out in the context of epizootological units within Kazakh economic entities and biomaterial for laboratory tests for pasteurellosis was selected. Pasteurella multocida isolates and strains were used in the experiments, and their cultural and morphological properties were studied. The obtained data from studies of the properties of isolated cultures in comparison with the characteristics of the reference strains gave grounds to attribute them to the Pasteurella genus. Based on the conducted study, epizootic visualization maps for cattle pasteurellosis for 2021 were developed.

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Section: Introductionmentioning

confidence: 99%

Development of Veterinary and Sanitary Measures for the Prevention of Pasteurellosis Infection in Cattle: The Case of the Republic of Kazakhstan

2023

Int J Vet Sci

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Responses of pro-inflammatory cytokines, acute phase proteins and cytological analysis in serum and cerebrospinal fluid during haemorrhagic septicaemia infection in buffaloes

Chung

Jesse

Marza

et al. 2019

Trop Anim Health Prod

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Sudden death is usually the main finding in field animals during haemorrhagic septicaemia outbreaks caused by Pasteurella multocida type B:2 that causes acute, fatal and septicaemic disease in cattle and buffaloes. This situation may be due to failure in early detection of the disease where early treatment of antibiotics may improve the prognosis of the animal and other surviving animals. Thus, there is a grey area on the knowledge on the potential usage of pro-inflammatory cytokines and acute phase proteins as early biomarkers in the diagnosis of haemorrhagic septicaemia. In addition, exploration of the cerebrospinal fluid during infection has never been studied before. Therefore, this study was designed to fill up the grey areas in haemorrhagic septicaemia research. Twenty-one buffalo calves were divided into seven treatment groups where group 1 was inoculated orally with 10 mL of sterile phosphatebuffered saline pH 7 which act as a negative control group. Groups 2 and 3 were inoculated orally and subcutaneously with 10 mL of 1012 colony-forming unit of P. multocida type B:2. Group 4 and 5 buffaloes were inoculated orally and intravenously with 10 mL of lipopolysaccharide broth. Groups 6 and 7 were administered orally and subcutaneously with 10 mL of outer membrane protein broth. During the post-infection period of 21 days, blood and cerebrospinal fluid were sampled for the analyses of pro-inflammatory cytokines, acute phase proteins and cytological examination. Buffalo calves infected with P. multocida and its immunogens via different routes of inoculation showed significant changes (p < 0.05) of proinflammatory cytokines, acute phase proteins and cytological changes in both the serum and cerebrospinal fluid. Buffalo calves from groups 3 and 7 showed the highest pro-inflammatory cytokines, whereas group 6 had the highest acute phase protein concentration and group 5 revealed the highest value for cytology changes. In summary, results obtained in this study could be used as a profiling study to add novel knowledge to the haemorrhagic septicaemia research as well as the development of biomarkers.

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Biomarkers, immune responses and cellular changes in vaccinated and non-vaccinated goats during experimental infection of M. haemolytica A2 under tropical conditions

Maqbool

Paul

Jesse

et al. 2021

Microbial Pathogenesis

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Host Cell and Antibody Response towards <i>Pasteurella Multocida</i> B2 Infection-A General Review

Cited by 4 publications

References 26 publications

Development of Veterinary and Sanitary Measures for the Prevention of Pasteurellosis Infection in Cattle: The Case of the Republic of Kazakhstan

Development of Veterinary and Sanitary Measures for the Prevention of Pasteurellosis Infection in Cattle: The Case of the Republic of Kazakhstan

Responses of pro-inflammatory cytokines, acute phase proteins and cytological analysis in serum and cerebrospinal fluid during haemorrhagic septicaemia infection in buffaloes

Biomarkers, immune responses and cellular changes in vaccinated and non-vaccinated goats during experimental infection of M. haemolytica A2 under tropical conditions

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