Host-derived protein profiles of human neonatal meconium across gestational ages
Yoshihiko Shitara,
Ryo Konno,
Masahito Yoshihara
et al.
Abstract:Meconium, a non-invasive biomaterial reflecting prenatal substance accumulation, could provide valuable insights into neonatal health. However, the comprehensive protein profile of meconium across gestational ages remains unclear. Here, we conducted an extensive proteomic analysis of first meconium from 259 newborns across varied gestational ages to delineate protein composition and elucidate its relevance to neonatal diseases. The first meconium samples were collected, with the majority obtained before feedin… Show more
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