“…The α-, β-, and γ-cyclodextrins are subclasses of cyclodextrins widely used for nanoencapsulation, and they could be differentiated by the presence of 6, 7, and 8 glucopyranose units, respectively, that determine the size of their internal cavity ( Szejtli, 1998 ; Saha et al, 2016 ; Jansook et al, 2018 ). These cyclodextrins have a truncated cone-shaped molecular form, and their hydrophobic cavities have a remarkable ability to form non-covalent inclusion complexes with a variety of compounds ( Lee et al, 2020 ; Pena et al, 2022 ). During the formation of an inclusion complex, water molecules are displaced to the outside of the lipophilic cavity, due to the presence of new lipophilic guest molecules that induce a new equilibrium ( Anaya-Castro et al, 2017 ).…”