Hybrid denture prosthesis have been used popularly in prosthodontics as a tooth replacement option. with some controversy. Hybrid dentures consist of one of the most novel options in the restoration of the edentulous arches. The implants are only placed only in the anterior region and the prosthesis is provided in the posterior region with the assistance of a cantilevered bar or framework. Conventionally the framework for such a prosthesis is fabricated using titanium or cobalt-chromium metal. Traditionally the frameworks were fabricated using metal casting. However, with the advent of digital dentistry CAD CAM frameworks have become very popular which have allowed the use of an array of materials such as zirconia,peek amongst other traditionally used metals.With a focus on materials used in the fabrication process of hybrid dentures, the goal of this study was to summarise the pertinent literature in this area.In conclusion, hybrid dentures seem like a viable treatment option which can be fabricated using multiple materials such as PEEK,zirconia,titanium,cast base metals, noble metals etc.