h i g h l i g h t sWe examined the pollutant exposureepoverty relationship in Ho Chi Minh, Vietnam. Personal exposures to particles and NO 2 were higher amongst the poor. Ambient levels poorly reflect personal exposures, in particular for poor residents. In addition to socioeconomic status, behavioral factors determined exposure levels. a b s t r a c t Socioeconomic factors often affect the distribution of exposure to air pollution. The relationships between health, air pollution, and poverty potentially have important public health and policy implications, especially in areas of Asia where air pollution levels are high and income disparity is large. The objective of the study was to characterize the levels, determinants of exposure, and relationships between children personal exposures and ambient concentrations of multiple air pollutants amongst different socioeconomic segments of the population of Ho Chi Minh City, Vietnam. Using repeated (N ¼ 9) measures personal exposure monitoring and determinants of exposure modeling, we compared daily average PM 2.5 , PM 10 , PM 2.5 absorbance and NO 2 concentrations measured at ambient monitoring sites to measures of personal exposures for (N ¼ 64) caregivers of young children from high and low socioeconomic groups in two districts (urban and peri-urban), across two seasons. Personal exposures for both PM sizes were significantly higher among the poor compared to non-poor participants in each district. Absolute levels of personal exposures were under-represented by ambient monitors with median individual longitudinal correlations between personal exposures and ambient concentrations of 0.4 for NO 2 , 0.6 for PM 2.5 and PM 10 and 0.7 for absorbance. Exposures of the non-poor were more highly correlated with ambient concentrations for both PM size fractions and absorbance while those for NO 2 were not significantly affected by socioeconomic position. Determinants of exposure modeling indicated the importance of ventilation quality, time spent in the kitchen, air conditioner use and season as important determinant of exposure that are not fully captured by the differences in socioeconomic position. Our results underscore the need to evaluate how socioeconomic position affects exposure to air pollution. Here, differential exposure to major sources of pollution, further influenced by characteristics of Ho Chi Minh City's rapidly urbanizing landscape, resulted in systematically higher PM exposures among the poor.