In 2017, the Chinese government created a policy on mandatory waste separation. Many communities and cities have created waste management institutions and appointed workers to supervise these actions. But there is little information about the situation in terms of the knowledge, attitudes, and practices of waste separation and any differences among regions and cities. Thus, the goal of this paper is to show the current status quo and any differences and to analyze their determinants, especially regarding cultural consumption. Based on online survey data collected in 2021, we found that knowledge in rural regions was lower than in urban regions, but there was no difference in attitudes or practices; the practices in pilot cities were better than in non-pilot cities, but the knowledge and attitudes showed no differences. Different cultural consumption patterns had different impacts on waste separation knowledge, attitudes, and practices. Based on the results, a policy related to culture should be enacted to improve efficiency and increase the action impacts to solve environmental and social issues.