Houston hurricane Harvey health (Houston-3H) study: assessment of allergic symptoms and stress after hurricane Harvey flooding

Oluyomi, Abiodun; Panthagani, Kristen; Sotelo, Jesus; Gu, Xiangjun; Armstrong, Georgina; Luo, Dan; Hoffman, Kristi L.; Rohlman, Diana; Tidwell, Lane G.; Hamilton, Winifred J.; Symanski, Elaine; Anderson, Kimberly A.; Petrosino, Joseph F.; Walker, Cheryl L.; Bondy, Melissa L.

doi:10.1186/s12940-021-00694-2

Cited by 35 publications

(29 citation statements)

References 28 publications

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“…Studies on the health effects of flooding events in the USA have been conflicting, and while there is a general trend towards a link between atopic disease and fungal exposure, at least in children, this is not clearcut and is not often related to risk of IgE sensitisation. [42][43][44]…”

Section: Dovepressmentioning

confidence: 99%

New Perspectives in the Diagnosis and Management of Allergic Fungal Airway Disease

Wardlaw¹,

Rick²,

Özyiğit³

et al. 2021

JAA

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Allergy to airway-colonising, thermotolerant, filamentous fungi represents a distinct eosinophilic endotype of often severe lung disease. This endotype, which particularly affects adult asthma, but also complicates other airway diseases and sometimes occurs de novo, has a heterogeneous presentation ranging from severe eosinophilic asthma to lobar collapse. Its hallmark is lung damage, characterised by fixed airflow obstruction (FAO), bronchiectasis and lung fibrosis. It has a number of monikers including severe asthma with fungal sensitisation (SAFS) and allergic bronchopulmonary aspergillosis/mycosis (ABPA/ M), but these exclusive terms constitute only sub-sets of the condition. In order to capture the full extent of the syndrome we prefer the inclusive term allergic fungal airway disease (AFAD), the criteria for which are IgE sensitisation to relevant fungi in association with airway disease. The primary fungus involved is Aspergillus fumigatus, but a number of other thermotolerant species from several genera have been implicated. The unifying mechanism involves germination of inhaled fungal spores in the lung in the context of IgE sensitisation, leading to a persistent and vigorous eosinophilic inflammatory response in association with release of fungal proteases. Most allergenic fungi, including Alternaria and Cladosporium species, are not thermotolerant and cannot germinate in the airways so only act as aeroallergens and do not cause AFAD. Studies of the airway mycobiome have shown that A. fumigatus colonises the normal as much as the asthmatic airway, suggesting it is the tendency to become IgE-sensitised that is the critical triggering factor for AFAD rather than colonisation per se. Treatment is aimed at preventing exacerbations with glucocorticoids and increasingly by the use of anti-T2 biological therapies. Anti-fungal therapy has a limited place in management, but is an effective treatment for fungal bronchitis which complicates AFAD in about 10% of cases.

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Section: Dovepressmentioning

confidence: 99%

New Perspectives in the Diagnosis and Management of Allergic Fungal Airway Disease

Wardlaw¹,

Rick²,

Özyiğit³

et al. 2021

JAA

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“…Health impacts from flooding can be physical or psychological. Physical outcomes include gastrointestinal illnesses, respiratory illnesses, skin rashes and infections and poisoning from exposure to chemical irritants [ 1 , 2 , 3 , 4 , 5 , 6 , 7 ]. Psychological distress and trauma are common among people who have experienced sudden flooding as a result of extreme weather events [ 8 , 9 , 10 ].…”

Section: Introductionmentioning

confidence: 99%

Recurrent Home Flooding in Detroit, MI 2012–2020: Results of a Household Survey

Larson

Gronlund

Thompson

et al. 2021

IJERPH

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Household flooding has wide ranging social, economic and public health impacts particularly for people in resource poor communities. The determinants and public health outcomes of recurrent home flooding in urban contexts, however, are not well understood. A household survey was used to assess neighborhood and household level determinants of recurrent home flooding in Detroit, MI. Survey activities were conducted from 2012 to 2020. Researchers collected information on past flooding, housing conditions and public health outcomes. Using the locations of homes, a “hot spot” analysis of flooding was performed to find areas of high and low risk. Survey data were linked to environmental and neighborhood data and associations were tested using regression methods. 4803 households participated in the survey. Flooding information was available for 3842 homes. Among these, 2085 (54.26%) reported experiencing pluvial flooding. Rental occupied units were more likely to report flooding than owner occupied homes (Odd ratio (OR) 1.72 [95% Confidence interval (CI) 1.49, 1.98]). Housing conditions such as poor roof quality and cracks in basement walls influenced home flooding risk. Homes located in census tracts with increased percentages of owner occupied units (vs. rentals) had a lower odds of flooding (OR 0.92 [95% (CI) 0.86, 0.98]). Household factors were found the be more predictive of flooding than neighborhood factors in both univariate and multivariate analyses. Flooding and housing conditions associated with home flooding were associated with asthma cases. Recurrent home flooding is far more prevalent than previously thought. Programs that support recovery and which focus on home improvement to prevent flooding, particularly by landlords, might benefit the public health. These results draw awareness and urgency to problems of urban flooding and public health in other areas of the country confronting the compounding challenges of aging infrastructure, disinvestment and climate change.

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“…Following Houston hurricane a survey was conducted which explored allergy and stress in the affected population. Results suggested that the affected population showed higher rate of allergies and high stress score (14). However association with cancer or longer follow-up of the population was not done as part of the study.…”

Section: % Of Patients Experiencedmentioning

confidence: 97%

Psychological traumatic events in the recent past and association with diagnosis of cancer

Shah¹,

Shah²

2021

LMRJ

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Emotional stress due to psychological trauma causes immune system dysfunction resulting in high risk of development of cancer. The study aimed to correlation psychological trauma in the past five years of cancer diagnosis. This study was a community based survey including cancer patients diagnosed with different cancers undergoing treatment or follow-up by using snowball sampling and questionnaire based technique. The study was conducted during a period of one year from December 2019 till December 2020. All recruited patients were requested for an interview. The results of the study showed a high rate of major psychological trauma among cancer patients. Sudden death of a close relative with and without trauma of natural disaster were high. The study conclude that risk of cancer development rises with major emotional trauma specially death of a close relative.

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Houston hurricane Harvey health (Houston-3H) study: assessment of allergic symptoms and stress after hurricane Harvey flooding

Cited by 35 publications

References 28 publications

New Perspectives in the Diagnosis and Management of Allergic Fungal Airway Disease

New Perspectives in the Diagnosis and Management of Allergic Fungal Airway Disease

Recurrent Home Flooding in Detroit, MI 2012–2020: Results of a Household Survey

Psychological traumatic events in the recent past and association with diagnosis of cancer

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