How accurate is fetal biometry in the assessment of fetal age?

Chervenak, Frank A.; Skupski, Daniel; Romero, Roberto; Myers, Mary Kay; Smith‐Levitin, Michelle; Rosenwaks, Zev; Thaler, Howard T.

doi:10.1016/s0002-9378(98)70477-6

Cited by 144 publications

(98 citation statements)

References 19 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…These studies often focus on a small set of (Queenan et al, 1980;Jeanty et al, 1984;Chervenak et al, 1998), or even single, estimators (Redfield, 1970;Quetel, 1981, 1982;Hadlock et al, 1982a,b,c;Anderson et al, 1996), and frequently limit the time period examined (e.g., 14 -22 weeks' gestational age; Chervenak et al, 1998).…”

mentioning

confidence: 99%

Fetal age: Methods of estimation and effects of pathology

Sherwood

Meindl

Robinson

et al. 2000

Am. J. Phys. Anthropol.

View full text Add to dashboard Cite

Accurate identification of fetal age is important in a wide variety of circumstances. Seventeen anthropometric and radiographic measurements were taken on fetuses between 15 and 42 weeks of gestational age, both with and without pathologic conditions. A full evaluation including radiographic, karyotypic, gross anatomic, and histologic examination of the fetus and placenta identified 72 individuals as nondysmorphic with no signs of chronic uterovascular insufficiency. These specimens served as the control group. Based on least-squares regressions of this group, age-estimation equations were calculated for all variables. Six models were adequately described by linear equations; the remaining 11 required a quadratic term. Based on standard error of the estimate (S(y:x)), skeletal measures proved the most accurate age estimators. Pathologic conditions were shown to have an influence on age estimation indicated by high levels of inaccuracy and, in some instances, significant bias.

show abstract

mentioning

confidence: 99%

Fetal age: Methods of estimation and effects of pathology

Sherwood

Meindl

Robinson

et al. 2000

Am. J. Phys. Anthropol.

View full text Add to dashboard Cite

show abstract

“…They showed that after the 36 th week, the total measurement of circumferences (head, thorax, femur length) was characteristic for better accuracy and a significant decrease of values of average error, standard deviation or maximum error in comparison with single parameter measurement. In turn, Chervenak et al [23] found that in the 2 nd trimester, the head circumference was the best determinant and accessory measurements of abdominal circumference and femoral bone length increased definition accuracy. Literature provides mathematical models of growth elaborated on the basis of ultrasound method measurements.…”

Section: Discussionmentioning

confidence: 99%

Assessment of Foetal Age on the Basis of the Selected Dimensions of the Thorax

Woźniak¹,

Kędzia²,

Dudek

2014

Adv Clin Exp Med

View full text Add to dashboard Cite

Background. The correct definition of foetal age is a substantial problem in forensic medicine, gynaecology, obstetrics and anthropology. Objectives. The goal of the study was the mathematical assessment of the foetal age with the use of thorax selected dimensions. Material and Methods. The material consisted of 110 foetuses aged 4-7 months of foetal life, including 50 females in the CRL range: 80-233 mm. The following methods were incorporated: preparation, anthropological, image digital acquisition, Image J computer system measurements and statistical analysis. For each foetus the following sizes were taken: crump-rump length -CRL (v-tub), total body length -v-pl as well as brachial circumference -BC, thoracic circumference -TC and clavicular length -CLA. Results. Six monofunctional mathematical models were elaborated: Bertalanffy growth curve, three Gompertz function based models and two exponential models to assess examined parameters increase along with t age. Model no. 3 for Gompertz function revealed the biggest consistency with v-pl measurements for every determination ratio R 2 = 0.9944 for exponential model R 2 = 0.9917. Multiple regression analysis was used to elaborate mathematical formula to assess the foetal age (determination factor R 2 = 0.9997) with BC, TC parameters. Conclusions. Examined parameters BC and TC were found useful in foetal age assessment in the evaluated age range. Elaborated mathematical model can be applied in clinical practice e.g. in foetal age ultrasound determination (Adv Clin Exp Med 2014, 23, 5, 805-811).

show abstract

“…The concern over adjusting a normal ultrasound date discrepancy is that aneuploid fetuses may be growthretarded, and therefore adjusting the dates by a smaller than expected GA on ultrasound could 'normalize' a fetus, thus lowering the likelihood of detection of aneuploidy. Recent work by Chervenak et al [18] suggests that the accuracy window of second-trimester estimates of GA are tighter than previously thought, such that the general rule of requiring a 14-to 17-day difference can probably be reduced to 10-14 days.…”

Section: Gestational Agementioning

confidence: 95%

Variability of Adjustments to Indices in Determining Patient Risk in Biochemical Screening

Brooks

Chik²,

O’Brien³

et al. 1999

Fetal Diagn Ther

View full text Add to dashboard Cite

It has long been appreciated that the measurement of biochemical parameters for prenatal screening for neural tube defects, and later aneuploidy, is not as simple as measuring hemoglobin or hematocrit. Early in the game, it was recognized that there are gestational age curves, and that since α-fetoprotein (AFP), for example, is a fetal product, its distribution varies as a function of maternal plasma volume, and therefore the weight of the mother. A number of different adjustment factors have been used for AFP and other parameters for years, with varying degrees of consistency and reliability. Here we review a number of adjustments that have been used, and try to give priority to those that have been most effective. Furthermore, laboratories and programs need to be cognizant that with newer parameters being added, the specifics of requirements will vary on a case-by-case parameter basis, and optimal screening can only be achieved with the appropriate adjustments.

show abstract

How accurate is fetal biometry in the assessment of fetal age?

Cited by 144 publications

References 19 publications

Fetal age: Methods of estimation and effects of pathology

Fetal age: Methods of estimation and effects of pathology

Assessment of Foetal Age on the Basis of the Selected Dimensions of the Thorax

Variability of Adjustments to Indices in Determining Patient Risk in Biochemical Screening

Contact Info

Product

Resources

About