Over the past two decades, significant work has been done to increase the opportunities for engineering students to develop an entrepreneurial mindset (EM). These have included curricular, cocurricular, and extracurricular activities on many campuses. This article describes efforts to build the EM comprehensively into the mechanical engineering curriculum at Ohio Northern University. While several frameworks have been proposed related to the EM, the work here is motivated by the Kern Entrepreneurial Engineering Network framework (KEEN). A core group of college faculty identified the institutional definitions of the KEEN student outcomes and identified courses for deployment of these outcomes to provide comprehensive, curriculum-wide exposure to the EM. This article discusses how the work was completed, incentive and reporting structures for onboarding faculty, the adopted strategies for program assessment of the EM outcomes, and efforts to ensure long-term sustainability of the curricular modifications. Observations, challenges, and unexpected benefits are discussed, as well as anticipated next steps for college-wide implementation.