Artificial Intelligence (AI) technology has revolutionized how we interact with information and entertainment, with ChatGPT, a language model developed by OpenAI, one of its prominent applications. However, there is limited knowledge of the psychological impact of interacting with ChatGPT. This study aims to investigate the relationships between trust in ChatGPT, user perception of ChatGPT, stereotype perception of ChatGPT, and two psychological outcomes: psychological well-being and self-esteem. The study hypothesizes that trust in ChatGPT, user perception of ChatGPT, and stereotype perception of ChatGPT have a positive direct relationship with self-esteem. Additionally, the study proposes that the relationship between trust in ChatGPT, user perception of ChatGPT, and psychological well-being is moderated by job anxiety. Using a survey design, data were collected from a sample of participants (n = 732), and the relationships between the variables were analyzed using regression analysis. The results indicate that stereotype perception of ChatGPT significantly predicts self-esteem, while user perception of ChatGPT and trust in ChatGPT have a positive direct relationship with self-esteem. The study also found that job anxiety moderates the relationship between user perception of ChatGPT and psychological well-being. The study provides important insights into the psychological effects of interacting with AI technology and highlights the role of job anxiety in moderating these effects. These findings have implications for the development and use of AI technology in various fields, such as mental health and human-robot interactions.