How Approaches to Drug Therapy for Malignant Tumors Have Changed (To the First Domestic Antitumor Drug Is Dedicated)

Abstract

In 1947 for the first time in the USSR in the Leningrad Institute of Oncology L.F. Larionov and and V.G. Nemets have developed and clinically tested the first domestic cytostatic embihin. Since that time more than 150 different anti-cancer agents and supportive care medications were widely investigated and used in current clinical practice in oncology and hematology in the frames of domestic and international studies. Nowadays basing on results of fundamental, clinical and experimental trials new high-effective medical approaches to systemic treatment such as targeted therapy and immunotherapy for patients with different malignant tumors are successfully studied and implemented.