How canola and sunflower oils affect lipid profile and anthropometric parameters of participants with dyslipidemia

Abstract

Background: Restricted intakes of saturated and trans-fatty acids and replacement with poly or monounsaturated fatty acids are emphasized in healthy diets. This study evaluates the effects of a six-month consumption of canola oil compared to sunflower oil on lipid profile and anthropometric parameters of people affected by dyslipidemia. Methods: This randomized controlled trial was conducted on 96 patients with dyslipidemia, who were randomly assigned into canola oil or the sunflower oil groups. The participants were instructed to record the contents of their daily meals, beverages, fruits, and snacks a day before treatment, at the second clinic visit, in the third month, and at the end of study (i.e., six months). Lipid profile and anthropometric parameters were compared between the two groups. Student t-test or Mann Whitney U test was used for statistical comparisons of variables between groups. Multivariate analysis was performed to adjust the confounding factor effects. Results: Of the enrolled participants, 44 (45.8%) were on sunflower oil diet and 52 (54.2%) on canola oil diet. We observed no change in anthropometric parameters and thus no significant difference between the two groups (p>0.05). Significant reductions in LDL-C (p<0.001), total cholesterol (p<0.001) and triglyceride levels (p<0.001), and significant elevation in HDL-C (p=0.008) were observed in canola oil group, as well as those who used sunflower oil. Conclusion: Dietary fats in the form of canola oil or sunflower oil effectively lower the serum cholesterol, LDL-C and triglyceride concentrations. They also result in an increase in serum concentration of HDL-C. These oils, however, did not modify general anthropometric parameters.

Consumption of Canola Oil vs. Other Common Oil(s) in Dyslipidemia Management among Urban Indian Adults

“…sunflower oil for 6 weeks. Both the groups showed significant decline in LDL (Canola (Saedi et al 2017). This was another key observation of our study since obesity (increased weight, BMI and WC) is a known risk factor for CVDs.…”

The Effect of Canola Oil on Body Weight and Composition: A Systematic Review and Meta-Analysis of Randomized Controlled Clinical Trials

“…These analyses revealed that CO ingestion does not significantly affect HC (WMD = −0.24 cm; 95% CI: −3.01, 2.54 cm, P = 0.867) (32,37,80), lean body mass (WMD = 0.01; 95% CI: −0.16, 0.19, P = 0.874) (31,33), or A:G ratio (WMD = −0.01; 95% CI: −0.03, 0.01, P = 0.271) (31,73).…”

“…CO was provided to participants using different methods: using a vehicle like foods (38,47,73,74,81) or high-CO diets (31,34,39,46,(77)(78)(79)(80)(82)(83)(84)(85). The edible oils used for the control groups and periods also varied: isocaloric diets based on SFAs (79,82,83,85), olive oil (46,77,78), sunflower oil (39,80), dairy fats (34), a blend of corn and safflower oil (31), and safflower (84). Some studies used diets supplemented with a specific amount of CO for the intervention group (45, 32, 33, 35-37, 75, 76), while the control groups consumed the same diets supplemented with an equivalent amount of sunflower oil (32,36), olive oil (45,33,35,76), or fish oil (75) or simply consumed a baseline diet (37).…”

“…Among 25 studies included in the systematic review, 8 were categorized as good quality (31,35,36,38,73,75,77,84), 6 were fair quality (45,32,47,79,82,83), and 11 were low quality (33,34,37,39,46,74,76,78,80,81,85). The details of the risk of bias in individual studies according to the domains used by the Cochrane Collaboration's tool are provided in Table 2.…”

“…Six studies with 481 participants were included in the metaanalysis (32,33,35,37,38,80). Supplemental Table 2 shows the overall effect of CO consumption on WC and by several subgroups.…”