How coffee affects metabolic syndrome and its components

Abstract

Metabolic syndrome, with its increasing prevalence, is becoming a major public health problem throughout the world. Many risk factors including nutrition play a role in the emergence of metabolic syndrome. Of the most-consumed beverages in the world, coffee contains more than 1000 components such as caffeine, chlorogenic acid, diterpenes and trigonelline. It has been proven in many studies that coffee consumption has a positive effect on chronic diseases. In this review, starting from the beneficial effects of coffee on health, the relationship between coffee consumption and metabolic syndrome and its components has been investigated. There are few studies investigating the relationship between coffee and metabolic syndrome, and the existing ones put forward different findings. The factors leading to the differences are thought to stem from coffee variety, the physiological effects of coffee elements, and the nutritional ingredients (such as milk and sugar) added to coffee. It is reported that consumption of coffee in adults up to three cups a day reduces the risk of Type-2 diabetes and metabolic syndrome.

Metabolic syndrome and lifestyle factors among type 2 diabetes mellitus patients in Dessie Referral Hospital, Amhara region, Ethiopia

“…This finding was supported by the findings from the general population, even-though finding among T2DM was not accessed [ 37 , 38 ]. Similarly, epidemiological reviews concluded that coffee consumption protects from MetS [ 39 , 40 ]. Studies suggested that several components of coffee had antihypertensive properties [ 41 , 42 ].…”

Coffee Intake Decreases Risk of Postmenopausal Breast Cancer: A Dose-Response Meta-Analysis on Prospective Cohort Studies

“…The metabolic syndrome, also known as insulin resistance syndrome, is a multifactorial disease well related to breast cancer risk of incidence and recurrence [ 71 , 72 ] with a crucial role in the activation of many endocrine and immune factors linked to breast cancer cell proliferation, survival and chemo-resistance. Among different nutritional approach aimed to revert metabolic syndrome in breast cancer patients, it was recently shown that consumption of coffee in adults up to three cups a day reduces the risk of type-2 diabetes, the metabolic syndrome as well as non-alcoholic fatty liver disease (NAFLD) [ 58 , 73 ]. Several studies showed that the association is rather stronger with the overall metabolic status than with individual components of the syndrome [ 67 , 74 ].…”

Coffee for Cardioprotection and Longevity

“…Coffee is a complex brew containing over 1,000 botanical compounds, many of which are biologically active, including caffeine (a central nervous system stimulant and bronchodilator), diterpenes (which can increase serum cholesterol), chlorogenic acid (which improves glucose metabolism), as well as melanoids, quinides, lignans, and trigonelline-all of which confer antioxidant and anti-inflammatory effects. 4…”