How DIRS is refining concepts

Abstract

Like the elaboration of good wine, which is dependent on excellent materials, well-honed techniques, and the passage of time, the evolution of our understanding of diseases and syndromes is dependent on similar features. The recognition of many neuroimmunologic diseases associated with autoantibodies is relatively recent. With time and experience (e.g., more patients and controls), concepts about disease mechanisms or even the syndromes associated with some autoantibodies are being refined or manifest the need for an extensive redefinition. In the current issue of N2, we have some articles on this theme.