2024
DOI: 10.3390/pathogens13110957
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How Does African Swine Fever Virus Evade the cGAS-STING Pathway?

Can Lin,
Chenyang Zhang,
Nanhua Chen
et al.

Abstract: African swine fever (ASF), a highly infectious and devastating disease affecting both domestic pigs and wild boars, is caused by the African swine fever virus (ASFV). ASF has resulted in rapid global spread of the disease, leading to significant economic losses within the swine industry. A significant obstacle to the creation of safe and effective ASF vaccines is the existing knowledge gap regarding the pathogenesis of ASFV and its mechanisms of immune evasion. The cyclic GMP–AMP synthase (cGAS)–stimulator of … Show more

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