Background: Studies have highlighted how public–private partnerships are characterized by a lack of transparency, low availability of data, low accountability, and, often, strong opportunism. All these factors do not allow potential interested parties to trust it. This undermines the possibility of good cooperation between the public and private sectors and has presented a great limit for the Public Private Partnerships (PPPs) diffusion. Several articles in the literature highlight, in general, the numerous advantages generated using the blockchain in different organizations. The adoption of blockchain in the operation of PPPs could be a solution to overcome the limitations encountered in public–private partnerships. The aim of this study is to propose a theoretical framework aimed at connecting two topics (PPPs and Blockchain)—analyzed separately by literature—to highlight how blockchain can correct the limitations inherent to the functioning of traditional PPPs. Methods: The authors applied a qualitative research method to examine the role of blockchain from a PPP perspective. The authors present a conceptual work in which they advance a theoretical framework by integrating and proposing new relationships between constructs and developing logical arguments for these associations. Through a problem-focused approach, besides presenting a solution to overcome the critical issues, the authors also put forward ideas to help fill a gap in the literature to date. Results: The study showed that blockchain can generate a major shift in the function of PPPs. On the one hand, it makes it possible to overcome many limitations that have hindered the development of partnerships, thus making it possible to spread them further, while on the other hand, it has a positive impact on the strategic role of PPPs in achieving sustainable development goals. Conclusions: Blockchain technology is considered very immature, probably because a single underlying standard does not exist and concepts are difficult to master. Based on state-of-the-art standards, blockchain has the potential to be considered a transformative or even disruptive innovation for PPPs.