How does radioactive iodine affect the nose?

Server, Ela Araz; Kırgezen, Tolga; Çelebi, Özlem Önerci; Muhammet, Yildiz; Ozgur, Yigit; Çermik, Tevfik Fikret

doi:10.1002/lary.26652

Cited by 2 publications

(3 citation statements)

References 15 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Server et al . 12 reviewed the effect of radioactive iodine therapy on nasal mucosa and nasal functions. The study included 41 patients (31 females and 10 males) who had received radioactive iodine therapy following papillary thyroid cancer.…”

Section: Discussionmentioning

confidence: 99%

“…Although it has been shown that radioactive iodine accumulation in the nose is normal and higher than in the mouth and parotid gland, 10 nasal complications have been neglected and only a limited number of studies have been published. [11][12][13] Those studies concluded that radioactive iodine caused loss of smell in patients, but the effect of dose was not investigated. This study aimed to determine whether the short-and long-term adverse effects on smell, taste and nose function are dependent on radioactive iodine dose.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Does the radioactive iodine dose affect smell, taste sensation and nose function?

et al. 2021

View full text Add to dashboard Cite

Objective To detect whether the adverse effects of post-operative radioactive iodine therapy following differentiated thyroid cancer on smell, taste and nasal functions were associated with radioactive iodine dose. Methods Fifty-one patients who had undergone total thyroidectomy because of differentiated thyroid cancer were divided into two groups depending on the post-operative radioactive iodine therapy dose: low dose group (50 mCi; 21 patients) and high dose group (100–150 mCi; 30 patients). The Sniffin’ Sticks smell test, the Taste Strips test and the 22-item Sino-Nasal Outcome Test were performed on all patients one week before therapy, and at two months and one year following therapy. Results Statistically significant differences were detected in the Sniffin’ Sticks test results, total odour scores, total taste scores and Sino-Nasal Outcome Test results between the assessment time points. There was no statistically significant difference between the low and high dose groups in terms of odour, taste or Sino-Nasal Outcome Test scores either before or after therapy. Conclusion Radioactive iodine therapy has some short- and long-term adverse effects on nasal functions and taste and odour sensations, which affect quality of life. These effects are not dose-dependent.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Does the radioactive iodine dose affect smell, taste sensation and nose function?

et al. 2021

View full text Add to dashboard Cite

show abstract

“…Treatment with RAI can produce early and late complications. The common early complications include swelling and discomfort in the neck, xerostomia, dry eye, abnormalities of taste and smell, dysphagia, nausea, vomiting, bone marrow suppression [90], gonadal damage (hypospermia or temporary amenorrhea/oligomenorrhea), nasal dryness and obstruction, and nasolacrimal obstruction [91][92][93][94][95][96]. The late complications include permanent salivary gland dysfunction, leukemia and secondary malignancy, pulmonary fibrosis, fertility problems [97][98][99][100][101][102].…”

Section: Effect Of Rai Treatment On Parathyroid Function For Dtc Patientsmentioning

confidence: 99%

Effect of Parathyroid Function After Thyroidectomy and Radioactive-Iodine Therapy for Thyroid Disease

Xiao¹,

Zhang²,

Li³

2019

BJSTR

View full text Add to dashboard Cite

Objective: Thyroidectomy and radioactive-iodine (RAI) treatment are two important methods for benign and malignant thyroid diseases. Thyroidectomy and RAI treatment may influence parathyroid gland function. This paper systematically reviewed the literatures on the effect of thyroidectomy and RAI on parathyroid gland function in patients with benign and maligant thyroid disease. Subjective and Methods:We searched PubMed for English literautres by using terms of "thyroidectomy" or "radioactive iodine" and "hyperthyroidism" or "Graves' disease" or "toxic multinodular goiter" or "toxic adenoma" or "differentiated thyroid carcinoma" and "parathyroid gland" or "calcium" or "parathyroid hormone" to review the effect of thyroidectomy and RAI on parathyroid gland function.Result: Thyroidectomy may lead to hypocalcaemia and hypoparathyroidism both for benign thyroid disease and DTC. For benign thyroid disease, RAI treatment may cause increasing PTH in the short term and may induce parathyroid adenoma or hyperplasia in the long term. For DTC patients, parathyroid gland function may transiently decline after RAI treatment. Conclusion:Thyroidectomy and RAI treatment may influence the parathyroid function in both benign and DTC patients. Thus, it is important to monitor PTH and blood calcium regularly in order to detect early abnormal parathyroid function for those patients.

show abstract

How does radioactive iodine affect the nose?

Abstract: 4. Laryngoscope, 127:2698-2702, 2017.

Cited by 2 publications

References 15 publications

Does the radioactive iodine dose affect smell, taste sensation and nose function?

Does the radioactive iodine dose affect smell, taste sensation and nose function?

Effect of Parathyroid Function After Thyroidectomy and Radioactive-Iodine Therapy for Thyroid Disease

Contact Info

Product

Resources

About