In recent times, workplace nepotism has become a prevalent issue facing small, medium and large companies; hence, it has turned out to be a major discussion among management practitioners and researchers. Besides, while we acknowledged the plentiful studies on workplace nepotism and employees’ job satisfaction nexus, there is limited literature on whether nepotism in the workplace does affect employees’ job satisfaction among healthcare companies in Nigeria. In view of the above, this study assessed workplace nepotism and employees’ job nexus of selected healthcare companies in Nigeria. The study used a sample of three hundred and ten (310) respondents, which were selected via a purposive sampling technique. Data obtained were analysed using descriptive (mean, standard deviation, skewness, kurtosis, and Pearson correlation), diagnostic (variance inflation factor) and inferential (multiple regression) statistical tools. Findings indicated significant and negative relationships between workplace nepotism dimensions (gender and ethnic divides) and employees’ job satisfaction. Given the findings, it was recommended that the management of healthcare companies should strive towards overseeing the divides in gender and ethnicity so as to cushion the effect on employees’ job satisfaction. Additionally, there is a need for healthcare companies’ management to set up measures aimed at fitting the divides in gender and ethnicity in order to encourage harmony among employees.