2009
DOI: 10.1007/978-3-642-02008-7_13
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How Many Bootstrap Replicates Are Necessary?

Abstract: Phylogenetic Bootstrapping (BS) is a standard technique for inferring confidence values on phylogenetic trees that is based on reconstructing many trees from minor variations of the input data, trees called replicates. BS is used with all phylogenetic reconstruction approaches, but we focus here on the most popular, Maximum Likelihood (ML). Because ML inference is so computationally demanding, it has proved too expensive to date to assess the impact of the number of replicates used in BS on the quality of the … Show more

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Cited by 441 publications
(405 citation statements)
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“…The parametric bootstrap method was applied to obtain the confidence intervals. A large enough replicate sample size of 10 4 was chosen to run the parametric bootstrap method (Pattengale et al 2009). …”
Section: Discussionmentioning
confidence: 99%
“…The parametric bootstrap method was applied to obtain the confidence intervals. A large enough replicate sample size of 10 4 was chosen to run the parametric bootstrap method (Pattengale et al 2009). …”
Section: Discussionmentioning
confidence: 99%
“…We performed a full tree inference under the general-time-reversible model allowing for site-specific rate variation and partition-wise optimised substitution rates coupled with a fast bootstrapping, where the number of necessary bootstrap replicates was determined by the extended majority rule consensus bootstop criterion (Pattengale et al 2009). To test for potential sampling or missing data bias – a number of Loranthaceae genera are only incompletely known for the five gene regions (File S3) – a gene-jackknifing procedure was applied, using a restricted data set with no missing gene region (full results included in the OSM; summarised in File S1).…”
Section: Methodsmentioning
confidence: 99%
“…We applied our method to the datasets we used in an earlier study of bootstrapping methods [13] and available at http://lcbb.epfl.ch/BS.tar.bz2. There are 10 datasets of single-gene and multi-gene DNA sequences, with anywhere from 125 to 994 taxa.…”
Section: Results On Biological Datamentioning
confidence: 99%