How sudden is a compelling desire to void? An observational cystometric study on the suddenness of this sensation

Wachter, Stefan De; Wyndaele, Jean‐Jacques

doi:10.1111/j.1464-410x.2007.07422.x

Cited by 30 publications

(26 citation statements)

References 19 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…However, this scale also had a high possibility of being confounded with individual perceptions. Other studies [12,13] have reported that normal and abnormal urgency symptoms cannot be effectively discriminated. Therefore, many researchers calculate the sum, mode, or mean USS scores from the questionnaires [3].…”

Section: Discussionmentioning

confidence: 99%

Association of Urinary Urgency and Delay Time of Micturition in Women With Overactive Bladder

Park

Huh

2014

Int Neurourol J

View full text Add to dashboard Cite

PurposeAccurately measuring urinary urgency is important for diagnosing overactive bladder (OAB) and quantifying improvements in treatment outcome. Various methods have been recommended for evaluating urinary urgency, but these methods assess individual perceptions and preferences. To overcome the subjectivity in measuring urinary urgency, we evaluated the relationship between uroflowmetric parameters and urinary urgency in women with OAB.MethodsConsecutive female patients with lower urinary tract symptoms (n=110) were prospectively enrolled in this study between April 2011 and September 2012. Individuals with a history of using medications that are known to affect bladder function were excluded. All enrolled patients completed uroflowmetry with a delayed time to voiding (T2V). After urination was completed, patients were asked whether they experienced any urinary hesitancy or urgency at that time.ResultsThe mean patient age was 56.1 years; 70 out of 110 patients reported some degree of urinary urgency. T2V decreased with increased urgency. Several uroflowmetric parameters were observed to have a significant correlation with urinary urgency. T2V had a meaningful correlation coefficient for individuals with urgency, regardless of the voided volume. There was no significant correlation between the presence of urinary hesitancy and T2V.ConclusionsWe believe that T2V would be a complementary tool for diagnosing and determining the degree of urinary urgency in women with OAB.

show abstract

Section: Discussionmentioning

confidence: 99%

Association of Urinary Urgency and Delay Time of Micturition in Women With Overactive Bladder

Park

Huh

2014

Int Neurourol J

View full text Add to dashboard Cite

show abstract

“…So, it is not straight forward to study neuro-physiologically sensations generated in the bladder in animal models using electrical recording from afferent nerves. The problem of linking afferent fibers to sensation is further compounded by the fact that the very nature of the sensations resulting from the afferents that reached consciousness is very difficult to describe 1 , 3 , 29 . Thus, questions relating to which fibers contribute to particular bladder sensations have been put to one side.…”

Section: Perspectives—a Classical Viewmentioning

confidence: 99%

The concept of peripheral modulation of bladder sensation

Eastham

Gillespie

2013

Organogenesis

View full text Add to dashboard Cite

It is recognized that, as the bladder fills, there is a corresponding increase in sensation. This awareness of the volume in the bladder is then used in a complex decision making process to determine if there is a need to void. It is also part of everyday experience that, when the bladder is full and sensations strong, these sensations can be suppressed and the desire to void postponed. The obvious explanation for such altered perceptions is that they occur centrally. However, this may not be the only mechanism. There are data to suggest that descending neural influences and local factors might regulate the sensitivity of the systems within the bladder wall generating afferent activity. Specifically, evidence is accumulating to suggest that the motor-sensory system within the bladder wall is influenced in this way. The motor-sensory system, first described over 100 years ago, appears to be a key component in the afferent outflow, the afferent “noise,” generated within the bladder wall. However, the presence and possible importance of this complex system in the generation of bladder sensation has been overlooked in recent years. As the bladder fills the motor activity increases, driven by cholinergic inputs and modulated, possibly, by sympathetic inputs. In this way information on bladder volume can be transmitted to the CNS. It can be argued that the ability to alter the sensitivity of the mechanisms generating the motor component of this motor-sensory system represents a possible indirect way to influence afferent activity and so the perception of bladder volume centrally. Furthermore, it is emerging that the apparent modulation of sensation by drugs to alleviate the symptoms of overactive bladder (OAB), the anti-cholinergics and the new generation of drugs the β3 sympathomimetics, may be the result of their ability to modulate the motor component of the motor sensory system. The possibility of controlling sensation, physiologically and pharmacologically, by influencing afferent firing at its point of origin is a “new” concept in bladder physiology. It is one that deserves careful consideration as it might have wider implications for our understanding of bladder pathology and in the development of new therapeutic drugs. In this overview, evidence for the concept peripheral modulation of bladder afferent outflow is explored.

show abstract

“…In some patients, urgency appears without any warning (on/off), whereas in others, it is preceded by the normal filling sensations and appears as continuum. 5 According to the data from these studies, different types of urgency might exist. In further support of this view are the differences in location where urgency can be felt: in some patients it is experienced suprapubically while in other perineally.…”

mentioning

confidence: 99%

Urgency: All or none phenomenon?

Wachter

Hanno

2010

Neurourology and Urodynamics

Self Cite

View full text Add to dashboard Cite

Urgency is the key symptom of a very prevalent symptom complex, the overactive bladder syndrome. Addressing urgency as a hallmark for detrusor overactivity is for physicians very comfortable, but appears to be an oversimplification of a very complex symptom entity. This overview tries to put the relevant literature on urgency against the question whether urgency is an all or none phenomenon, and summarizes the current views on how urgency is perceived.

show abstract

How sudden is a compelling desire to void? An observational cystometric study on the suddenness of this sensation

Cited by 30 publications

References 19 publications

Association of Urinary Urgency and Delay Time of Micturition in Women With Overactive Bladder

Association of Urinary Urgency and Delay Time of Micturition in Women With Overactive Bladder

The concept of peripheral modulation of bladder sensation

Urgency: All or none phenomenon?

Contact Info

Product

Resources

About