How to Care and Minimize the Sequelae of Lower Extremity Lymphedema

Bobrek, Katherine; Nabavizadeh, Reza; Nabavizadeh, Behnam; Master, Viraj

doi:10.1016/j.soncn.2022.151270

Cited by 1 publication

(2 citation statements)

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“…The recommendation that CDT is most effective in the early stages of HNL and less effective during the chronic period, supports the use of CDT in early intervention management, as well as the potential use of alternative modalities for effective treatment [16]. It is noteworthy that HNC patients are currently referred for HNL when their symptoms are more severe, which contradicts previous research indicating that early intervention is essential for positive treatment outcomes [8,17]. There is clearly a dearth of direction within the literature surrounding HNL management and reviews have shown the current standard of care for HNL is varied throughout the world, with the UK having no standard clinical pathway, single modality treatment or process of referral [8].…”

Section: Introductionmentioning

confidence: 99%

“…CDT consists of two phases with an intensive therapist led programme and maintenance phase carried out by HNC survivors [15]. Despite CDT being deemed the gold standard approach, there is limited knowledge surrounding its effectiveness [17]. Alternative treatment modalities are indicated in the literature with positive outcomes, highlighting the lack of consensus regarding the treatment of HNL.…”

Section: Introductionmentioning

confidence: 99%

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Evaluating the effects of lymphoedema management strategies on functional status and health-related quality of life following treatment for head and neck cancer: Protocol for a systematic review

Mullan,

Blackburn,

Lorimer

et al. 2024

PLoS ONE

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Introduction/Background Patients living with and after head and neck cancer often experience treatment-related consequences. Head and neck lymphoedema can be described as a common chronic side effect of head and neck cancer and recognised as a contributing factor to impairment of functional status, symptom burden and health-related quality of life. The effects of head and neck lymphoedema can limit patients’ involvement in daily activities and alter their appearance, increasing symptom burden and negatively affecting health-related quality of life. Objective The protocol outlines the rationale and aims for the systematic review. The main aim of the systematic review is to identify and systematically synthesise the literature on the effectiveness of head and neck lymphoedema management strategies, on both function status and health-related quality of life for head and neck cancer patients. Methods and analysis This protocol will be conducted according to the PRISMA-P guidelines. Electronic databases will be systematically searched using MEDLINE via Ovid and PubMed, CINAHL, Cochrane Central Register of Controlled Trials and Scopus. Inclusion criteria will involve intervention studies for head and neck lymphoedema management, English language, and adult human participants following head and neck cancer. The software Covidence will be used to export, manage, and screen results. Risk of bias and quality will be assessed in included studies using the Cochrane Handbook of Systematic Reviews of Intervention risk of bias and GRADE tools. A meta-analysis will be performed if there are sufficient homogenous studies. Alternatively, a narrative synthesis will be completed on study findings. Ethics and dissemination No ethical approval is required as the study does not involve patient and public involvement. The findings of the review will be disseminated in conferences and submitted for approval to be published in a peer-reviewed journal. Prospero registration number CRD42022378417. (S1 Appendix).

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