How to characterize non‐hypervascular hepatic nodules on contrast‐enhanced computed tomography in chronic liver disease: Feasibility of contrast‐enhanced ultrasound with a microbubble contrast agent

Yoshizumi, Hiroaki; Maruyama, Hitoshi; Okugawa, Hidehiro; Kobayashi, Satoshi; Akiike, Taro; Yoshikawa, Masaharu; Ebara, Masaaki; Yokosuka, Osamu; Matsutani, Shoichi; Kondo, Fukuo; Kamiyama, Naohisa

doi:10.1111/j.1440-1746.2007.05184.x

Cited by 11 publications

(3 citation statements)

References 52 publications

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“…Contrast medium injection addition to a conventional ultrasound study increases considerably accuracy and diagnostic confidence [11][12][13], therefore imposing CEUS application in liver focal lesions characterization detected at conventional ultrasound. Furthermore, it is reported CEUS application after non-diagnostic investigations (CT, MRI or CT-PET) [14][15][16][17][18][19].…”

Section: Discussionmentioning

confidence: 99%

Contrast enhancement ultrasound application in focal liver lesions characterization: a retrospective study about guidelines application (SOCEUS–CEUS survey)

et al. 2015

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Section: Discussionmentioning

confidence: 99%

Contrast enhancement ultrasound application in focal liver lesions characterization: a retrospective study about guidelines application (SOCEUS–CEUS survey)

et al. 2015

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“…The great advances in radiologic imaging of the last two decades have focused attention on hepatic nodular lesions 12. Differential diagnosis of hepatic nodules include hepatocellular carcinoma, focal nodular hyperplasia, hepatic adenoma, regenerative nodule, focal fatty change, and hemangioma.…”

Section: Discussionmentioning

confidence: 99%

Discrete Hypoechoic Ring in Hepatic Cavernous Hemangioma Resembling a Malignant Tumor: Correlation with Histologic Features

Choi

Baek²,

Jeong³

et al. 2009

Gut Liver

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Differential diagnoses of hepatic nodules include hepatocellular carcinoma, focal nodular hyperplasia, hepatic adenoma, regenerative nodule, focal fatty changes, and hemangioma. However, differentiation of these nodules can often be difficult. Hemangiomas are frequently encountered during ultrasonogram incidentally and can be diagnosed easily because they have an almost distinctive sonographic appearance: a homogeneous hyperechogenicity and discrete posterior acoustic enhancement. They also sometimes have atypical findings, for example an internal echogenicity including hypoechogenicity, heterogeneous echogenicity, hyperechoic rim, central hypoechogenicity due to various changes (e.g., internal hemorrhage, necrosis, thrombosis, myxomatous change, and fibrosis), and (rarely) calcification. We report herein the case of an atypical hemangioma presenting with a hypoechoic peripheral ring, mimicking a hepatic malignancy. To our knowledge, there have been no other reports demonstrating a cavernous hemangioma with a discrete hypoechoic ring and without a pseudocapsule.

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“…[55][56] The recent study reported that intensity analysis of contrast enhancement with Levovist was useful method for the characterization of non-hypervascular small hepatic nodules, regenerative nodule from HCC. 57 However, the diagnostic ability of contrastenhanced US in the early diagnosis of HCC and discrimination of dysplastic nodules from HCC has not been established. At present, percutaneous needle biopsy under US-guidance may be frequently required for the characterization of small hepatic lesions in patients with chronic liver diseases.…”

Section: Characterization Of Focal Liver Lesionsmentioning

confidence: 99%

Contrast-Enhanced Ultrasonography: A Recent Application for the Diagnosis and Treatment of Hepatocellular Carcinoma

2008

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Hepatocellular carcinoma has a decisive influence on the prognosis of cirrhotic patients, and the use of imaging modalities is essential for the screening, diagnosis and treatment of hepatocellular carcinoma. Ultrasound plays a major role among them, because it provides real-time and non-invasive observation by a simple and easy technique. In addition, ultrasound-guided needle puncture methods are frequently required for the diagnosis and/or treatment process of hepatocellular carcinoma. The development of digital technology has led to the detectability of blood flow by color Doppler ultrasound, and the sensitivity for tumor vascularity has shown remarkable improvement with the introduction of microbubble contrast agents. Moreover, near real-time three-dimensional ultrasound images are now available. These advancements in the ultrasound field have led to rapid progress in hepatocellular carcinoma management, and continuing advances are expected. This article reviews the current application of contrast-enhanced ultrasound for hepatocellular carcinoma in clinical practice.JNMA J Nepal Med Assoc. 2008 Jul-Sep;47(171):156-166.

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How to characterize non‐hypervascular hepatic nodules on contrast‐enhanced computed tomography in chronic liver disease: Feasibility of contrast‐enhanced ultrasound with a microbubble contrast agent

Abstract: CEUS with Levovist may be an alternative to biopsy to characterize small, non-hypervascular hepatic nodules on CECT in patients with CLD.

Cited by 11 publications

References 52 publications

Contrast enhancement ultrasound application in focal liver lesions characterization: a retrospective study about guidelines application (SOCEUS–CEUS survey)

Contrast enhancement ultrasound application in focal liver lesions characterization: a retrospective study about guidelines application (SOCEUS–CEUS survey)

Discrete Hypoechoic Ring in Hepatic Cavernous Hemangioma Resembling a Malignant Tumor: Correlation with Histologic Features

Contrast-Enhanced Ultrasonography: A Recent Application for the Diagnosis and Treatment of Hepatocellular Carcinoma

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