Peer-review is the core of the editorial process and the basis of the publication system. The quality of peer-review depends on the quality of the peer-reviewers. Peer reviewers are supposed to ensure that journals publish high-quality science by evaluating manuscripts and offering suggestions for improvement. Peer-reviewers are typically selected based on their expertise in the areas of research associated with the submitted manuscripts. Although being a peer-reviewer is sometimes frustrating, communication between authors, editors and reviewers in the peer-review process determines the eventual success of the publication; this communication should be formal, constructive, honest and polite [1, 2]. Specific standards of formal and ethical writing are necessary for peer-review. These standards should be maintained throughout the review process of any submitted paper in any particular journal. Peer-review is considered a biased process with identified defects [3-11]; some peer-reviewers are too young with limited experience, not all are equally skilled in the peer-review process, and very few have had a formal training and assessment methods for peer-review [1, 12, 13]. A growing body of quantitative evidence showed violations of objectivity and bias in the peer review process for reasons based on author attributes such as language, institutional affiliation, nationality, and others, authors' identity such as gender and sexuality, and reviewers' perceptions of the field such as territoriality within field, personal gripes with authors, scientific dogma, discontent/distrust of methodological advances [14, 15]. Occasionally, reviewers' comments are rude or unprofessional; in a study, more than half of 1106 anonymous respondents reported receiving at least one "unprofessional" review, and a majority of those said they had received multiple problematic comments including comments tended to personally target a scientist, lack constructive criticism, or unnecessarily harsh or cruel [15]. This editorial note aims to communicate to the readers of the journal the unified set of rules for a good and bad peer-review, and to emphasize on the avoidance and consequences of a rude peer-review.