How to fight with heart diseases

Abstract

The 2010 dietary cholesterol recommendations were derived from guidelines established in the 1960s, when little scientific evidence was present, other than the possible association between saturated fat and dietary cholesterol, as well as animal studies, in which cholesterol was fed in amounts that exceeded typical or normal intakes. Aim of this research was to compare individual and combined effects of Ispaghola and Anjeer in primary as well as secondary hyperlipidemia. It was single blind placebo-controlled research work, conducted from January 2017 to April 2017 at General Hospital, Lahore, Pakistan. One hundred male and female hyperlipidemic patients were selected for research, age range from 20 to 65 years. Inclusion criteria were primary, secondary hyperlipidemic patients. Written and explained consent was taken from all participants and approved by research ethics committee of the hospital. Patients were divided in four equal groups, comprising 25 patients in each group. Their baseline systolic/diastolic blood pressure and lipid profile was estimated and kept in individual's folder. Group-I was on Ispaghula 10 grams, group-II was on 10 grams Anjeer, and group-III was advised to take 10 grams Ispaghula and 10 grams Anjeer in combination for 3 months. Group-IV was on placebo therapy. After 3 months when results were compiled and analyzed statistically, it was observed that Ispaghula decreased LDL-c significantly with p-value <0.05, Anjeer decreased LDL-c significantly with p-value <0.01. When both herbs were combinely given, they reduced systolic BP with p-value <0.01, LDL-c reduced highly significantly with p-value <0.001, and HDL-c increased significantly with p-value <0.05. It was concluded from the study that Ispaghula and Anjeer have LDL-c lowering potential if given separately. When used in combination they reduce systolic BP, LDL-c, and increase HDL-c.