How to reduce the antibacterial load in the treatment of acute tonsillitis and pharyngitis? Possible tactics and practical approaches

Мескина, Е. Р.; Сташко, Т. В.

doi:10.17116/otorino20208506190

Cited by 4 publications

(1 citation statement)

References 75 publications

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“…It is worth noting that β- hemolytic Group A Streptococcus , a kind of Streptococcus , can trigger more severe symptoms and complications, such as postinfection systemic complications, acute rheumatic fever, and poststreptococcal glomerulonephritis [ 9 , 10 ]. At present, there are no specific drugs for the treatment of viral pharyngitis and tonsillitis, while antibiotics are mainly used to prevent complications and secondary infection in bacterial pharyngitis and tonsillitis [ 11 ]. However, antibiotic resistance and toxic side effects, especially in children, severely limit prevention and treatment in the clinic [ 12 ].…”

Section: Introductionmentioning

confidence: 99%

Pharmacological effects and mechanism of Kaihoujian Throat Spray (children's type) in the treatment of pediatric acute pharyngitis and tonsillitis

Pang

Zhao

Peng

et al. 2023

Heliyon

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Section: Introductionmentioning

confidence: 99%

Pharmacological effects and mechanism of Kaihoujian Throat Spray (children's type) in the treatment of pediatric acute pharyngitis and tonsillitis

Pang

Zhao

Peng

et al. 2023

Heliyon

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New effects of a topical antimicrobial (agent) in the treatment of acute tonsillopharyngitis

Ovchinnikov,

Miroshnichenko,

Nikolaeva

2023

Vestn. otorinolaringol.

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Modern aspects of treatment of acute tonsillopharyngitis

Vladimirova,

Lazareva,

Martynova

2024

Medicinskij sovet

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Introduction. Primary referral for infectious and inflammatory diseases of the pharynx reaches 30%.Aim. To study the effectiveness of ambazon in patients with acute tonsillopharyngitis.Materials and methods. The study was conducted at the SCDC Clinics of the Samara State Medical University and the CDC “Persona-Med” LLC in 75 patients (45.9 ± 11.2 years old) with acute tonsillopharyngitis (ATP). The main group (Group I, n = 48) additionally received ambazon, 1 tablet for resorption 15 minutes after meals 4 times a day for 4 days. The control group (Group II, n = 27) received symptomatic therapy. On the 1st, 2nd and 4th day, the complaint of sore throat was assessed using a visual analogue scale (VAS), the frequency of additional complaints, and the pharyngoscopic picture using a 4-point scale.Results and discussion. On the 2nd day, the severity of sore throat according to VAS in group I was 3.5 ± 0.2 points, in group II 4.9 ± 0.3 points (p < 0.05). On the 4th day, the severity of sore throat in group I had lower values 1.1 ± 0.1 points, in group II 2.9 ± 0.1 points (p < 0.05). On the 2nd day, complaints of a sensation of a foreign body in the oropharynx and discomfort when swallowing in group I amounted to 27.1% and 45.8%, and in group II 77.8% and 66.7%, respectively. The pharyngoscopic picture in group I was characterized by a decrease in the severity of edema and hyperemia of the pharyngeal mucosa (score of 1.3 ± 0.3 points and 1.1 ± 0.2 points), in group II 2.1 ± 0.3 points and 2.9 ± 0.4 points, respectively. On the 4th day, the pharyngoscopic picture in group I returned to normal, while in group II, hyperemia and edema of the mucosa and an increase in regional lymph nodes persisted.Conclusions. The use of ambazon in the treatment of ATP allows to reduce the severity of the pain symptom, reduce the frequency of additional complaints and normalize the pharyngoscopic picture.

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How to reduce the antibacterial load in the treatment of acute tonsillitis and pharyngitis? Possible tactics and practical approaches

Cited by 4 publications

References 75 publications

Pharmacological effects and mechanism of Kaihoujian Throat Spray (children's type) in the treatment of pediatric acute pharyngitis and tonsillitis

Pharmacological effects and mechanism of Kaihoujian Throat Spray (children's type) in the treatment of pediatric acute pharyngitis and tonsillitis

New effects of a topical antimicrobial (agent) in the treatment of acute tonsillopharyngitis

Modern aspects of treatment of acute tonsillopharyngitis

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