How vector-borne disease shaped the course of human history

Athni, Tejas S.; Shocket, Marta S.; Caldwell, Iain R.; Caldwell, Jamie M.; Childress, Jasmine N.; Childs, Marissa L.; Couper, Lisa I.; Leo, Giulio De; Kirk, Dudley; MacDonald, Andrew; Nova, Nicole; Olivarius, Kathryn; Pickel, David; Winokur, Olivia C.; Young, Hillary S.; Cheng, Jack Chin Pang; Grant, Elizabeth; Kurzner, Patrick M.; Kyaw, Saw; Lin, Bradford; López, Ricardo Castillo; Massihpour, Diba S.; Olsen, Erica; Roache, Maggie; Ruiz, Angie; Schultz, Emily A.; Shafat, Muskan; Spencer, Rebecca L.; Mordecai, Erin A.

doi:10.22541/au.159135318.82566392

Cited by 2 publications

(2 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Vector-borne diseases are caused by infectious agents transmitted by living organisms, called vectors, frequently insects. These diseases represent a significant threat to global human health [1], causing diseases such as malaria, dengue, yellow fever, Zika, trypanosomiasis, and leishmaniasis [2]. Vector-borne human diseases are responsible of more than 17% of all human infectious diseases, causing millions of cases and more than 700 000 deaths annually [3].…”

Section: Introductionmentioning

confidence: 99%

Vector-borne diseases with nonstationary vector populations: The case of growing and decaying populations

2022

View full text Add to dashboard Cite

Section: Introductionmentioning

confidence: 99%

Vector-borne diseases with nonstationary vector populations: The case of growing and decaying populations

2022

View full text Add to dashboard Cite

“…Vector-borne diseases are caused by infectious agents transmitted by living organisms, called vectors, frequently arthropods. These diseases represent a significant threat to global human health (Athni et al, 2020), causing diseases such as malaria, dengue, yellow fever, Zika, trypanosomiasis and leishmaniasis (Schumacher & Campbell, 2018). Vector-borne human diseases are responsible of more than 17% of all human infectious diseases, causing millions of cases and more than 700 000 deaths annually (WHO).…”

Section: Introductionmentioning

confidence: 99%

Vector-borne diseases with non-stationary vector populations: the case of growing and decaying populations

Giménez-Romero¹,

Rosa²,

Matías³

2022

Preprint

View full text Add to dashboard Cite

Since the last century, deterministic compartmental models have emerged as powerful tools to predict and control epidemic outbreaks, in many cases helping to mitigate their impacts. A key quantity for these models is the so-called Basic Reproduction Number, R 0 , that measures the number of secondary infections produced by an initial infected individual in a fully susceptible population. Some methods have been developed to allow the direct computation of this quantity provided that some conditions are fulfilled, such that the model has a pre-pandemic disease-free equilibrium state. This condition is only fulfilled when the populations are stationary. In the case of vector-borne diseases, this implies that the vector birth and death rates need to be balanced, what is not fulfilled in many realistic cases in which the vector population grow or decrease. Here we develop a vector-borne epidemic model with growing and decaying vector populations and study the conditions under which the standard methods to compute R 0 work and discuss an alternative when they fail. We also show that growing vector populations produce a delay in the epidemic dynamics when compared to the case of the stationary vector population. Finally, we discuss the conditions under which the model can be reduced to the SIR model with fewer compartments and parameters, which helps in solving the problem of parameter unidentifiability of many vector-borne epidemic models.

show abstract

How vector-borne disease shaped the course of human history

Cited by 2 publications

References 0 publications

Vector-borne diseases with nonstationary vector populations: The case of growing and decaying populations

Vector-borne diseases with nonstationary vector populations: The case of growing and decaying populations

Vector-borne diseases with non-stationary vector populations: the case of growing and decaying populations

Contact Info

Product

Resources

About