Cone Beam Computer Tomography CT Computer Tomography CTV Clinical Target Volume Relevance Include Exclude Studies that specifically investigated the processes used during clinical decision-making. These can be carried out in the natural or simulated environment. Studies that specifically investigated image interpretation during diagnostic review and reporting. Seminal texts related to general decision-making theory to be read to inform the wider discussion. Decision-making studies unrelated to the clinical setting. Ethics Include Exclude Studies where ethical approval has been sought and granted where relevant. Studies where consideration of ethical approval is not evident. The search process is shown in Figure 2.0 using a PRISMA flow diagram (Moher, Liberati, Tetzlaff, & Altman, 2009). The search identified 82 articles that met the search criteria. The majority of articles were discussion papers and non-systematic literature reviews (n=58). These articles were used to form some of the underpinning theoretical descriptions in the chapter, but did not meet the minimum requirements of the relevant SIGN quality checklist. The remaining 24 articles were case studies that typically investigated clinical reasoning in a specific setting and these underwent full review. Despite being outside of the inclusion criteria on the basis of date, Fonteyn and Grobe (1992) was identified as a seminal article during the review process and so was included for full review. An overview of the articles that underwent full review are shown in Appendix 1.