HPLC analysis and anti-inflammatory, antinociceptive, healing and antidepressant properties of Anchusa italica Retz extracts

Khomsi, Mostafa El; Hmamou, Anouar; Oubbadi, Rabab El; El houda Tahiri, Nor; Kara, Mohammed; Amar, Aya; Mesfioui, Abdelhalim; Hmouni, Driss

doi:10.1016/j.phyplu.2023.100518

Cited by 2 publications

(1 citation statement)

References 47 publications

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“…Additionally, underdeveloped nations have regarded medicinal plants as a vital treatment resource for various diseases due to their possession of diverse biological activities and a wide array of chemical structures. This is attributed to their content of metabolites and bioactive molecules, including coumarins, alkaloids, polyphenols, mucilages, tannins, and terpenes (Cock et al, 2018;El Khomsi et al, 2022;Hmamou et al, 2024Hmamou et al, , 2023bHmamou et al, , 2023aKhomsi et al, 2024Khomsi et al, , 2022.…”

Section: Introductionmentioning

confidence: 99%

Geographical Origin and Solvent Type Impact on<i> Inula Viscosa</i> (L.) Aiton Grown in El Menzel, Morocco – Insights into Bioactivity and Applications

Tlemcani,

El Ouadrhiri,

Hmamou

et al. 2024

Ecol. Eng. Environ. Technol.

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Geographical origin and environmental factors have a significant impact on the constituents and the biological properties of medicinal and aromatic plants. Herein, the Inula viscosa plant grown in El Menzel -Morocco were investigated with a focus on the impact of geographical province and solvent type on the mass yield and the biological activities of plant extracts. Chemical composition was characterized by gas chromatography/mass spectrometry (GC/MS). Antimicrobial activity was determined using the disk diffusion method and the microdilution test against eight clinical fungal, Gram-positive and Gram-negative bacterial isolates. The chemical composition results showed that the plant has good nutritional quality in terms of protein, carbohydrates, lipids and dietary fiber. In fact, alkaloids and saponisides are the most predominant chemical compounds in Inula vuscosa. Meanwhile, eighty volatile compounds were identified, representing 95% of the total essential oil content, the main component of which is tetra-pentacontane (11.26%). Furthermore, results showed high antioxidant activity, with efficacy increasing in the order: essential oil > chloroform extract > ethereal extract > ethanolic extract. In addition, both chloroformic extract and essential oil demonstrated significant antibacterial activity against all strains tested. This study highlights the influence of geographical variations and extraction solvents on the bioactivity of Inula viscosa, offering insights into its potential applications in pharmacology and nutraceuticals.

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Section: Introductionmentioning

confidence: 99%

Geographical Origin and Solvent Type Impact on<i> Inula Viscosa</i> (L.) Aiton Grown in El Menzel, Morocco – Insights into Bioactivity and Applications

Tlemcani,

El Ouadrhiri,

Hmamou

et al. 2024

Ecol. Eng. Environ. Technol.

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Anti-Aging Effects of Flavonoids from Plant Extracts

Păcularu-Burada,

Cîrîc,

Begea

2024

Foods

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Aging is a natural and irreversible process, affecting living organisms by negatively impacting the tissues’ and cells’ morphology and functionality and consequently being responsible for aging-related diseases. Taking into account the actual preoccupations of both consumers and researchers, healthy anti-aging alternatives are being intensively studied in order to address such concerns. Due to their functional features, plant flavonoids can be considered valuable nutraceuticals. This paper highlights the possibilities to use flavonoids extracted from various plants for their anti-aging potential on the skin, brain, and heart. Moreover, their anticarcinogenic, anti-inflammatory, and anti-diabetic properties are summarized, along with the senescence-associated mechanisms. Both the nutraceutical and cosmeceutical fields are continuously developing and flavonoids originating from plants are promising candidates to obtain such products. Thus, the bioactive compounds’ extraction and their subsequent involvement in innovative product manufacturing must be carefully performed while being aware of the various intrinsic and extrinsic factors that may affect the phytochemicals’ structures, bioavailability, and health effects.

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HPLC analysis and anti-inflammatory, antinociceptive, healing and antidepressant properties of Anchusa italica Retz extracts

Cited by 2 publications

References 47 publications

Geographical Origin and Solvent Type Impact on<i> Inula Viscosa</i> (L.) Aiton Grown in El Menzel, Morocco – Insights into Bioactivity and Applications

Geographical Origin and Solvent Type Impact on<i> Inula Viscosa</i> (L.) Aiton Grown in El Menzel, Morocco – Insights into Bioactivity and Applications

Anti-Aging Effects of Flavonoids from Plant Extracts

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