HPV condylomatosis region treated with multiple sessions of MAL-PDT: A case report

Stringasci, Mirian Denise; Buzzá, Hilde Harb; Arruda, Semira Silva de; Crestana, Rita Helena Schiavone; Bagnato, Vanderlei Salvador; Inada, Natália Mayumi

doi:10.1016/j.pdpdt.2020.101812

Cited by 4 publications

(2 citation statements)

References 5 publications

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“…Comparing to traditional clinical protocols of aPDT [40][41][42][43][44][45], these external light doses may seem too high for photodynamic therapy. However, a large part of this energy is reflected at the surface and being absorbed by the different biological tissues located in the thoracic cage, such as skin, subcutaneous fat, muscle, ribs and among others.…”

Section: Discussionmentioning

confidence: 96%

Photodynamic inactivation ofStreptococcus pneumoniaewith external illumination at 808 nm through the ex vivo porcine thoracic cage

Tovar

Kassab

Buzzá

et al. 2021

Journal of Biophotonics

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Pneumonia is responsible for high mortality rates around the world, and its major treatment is based on antibiotic treatment.Antimicrobial resistance has been increasing in the last years, resulting in relevant public health concern. A promising alternative for pneumonia is antimicrobial photodynamic therapy. The purpose of this study was to investigate whether 808 nm wavelength is able to be transmitted through the biological tissues of the thoracic wall and be delivered in enough energy inside the cage to activate indocyanine green and promote photodynamic response. A light source panel was developed composed of 200 lasers centered at 808 nm with an irradiance of 77.8 ± 10.0 mW/cm 2 and tested in an ex vivo tho-

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Section: Discussionmentioning

confidence: 96%

Photodynamic inactivation ofStreptococcus pneumoniaewith external illumination at 808 nm through the ex vivo porcine thoracic cage

Tovar

Kassab

Buzzá

et al. 2021

Journal of Biophotonics

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“…Besides, ALA is the only topical photosensitizer approved in China, therefore, the efficacy of PDT for genital warts in other countries or with other photosensitizers remains unclear. Though several studies from different countries have reported successful treatment of genital warts with methylaminolevulinate-PDT [36,37], further well-designed RCT studies are still limited to evaluate the efficacy and safety of PDT in these conditions. These factors contributed to the bias of this study.…”

Section: Discussionmentioning

confidence: 99%

Topical photodynamic therapy for genital warts: Systematic review and meta‐analysis

Zhi

Wang

Zhang

et al. 2022

Transl Biophotonics

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High recurrence rate and adverse effects were common shortcomings in treatments for genital warts, but a number of clinical studies have found that photodynamic therapy (PDT) had some unique superiority compared to other treatments. This study aims to evaluate the efficacy and safety of PDT for genital warts in comparison to alternative treatments. Seven databases and http://clinicaltrials.gov were searched and seven randomized controlled trials were finally included. There was no significant difference in clearance rate of urethral lesions between the PDT group and the CO2 laser therapy (CO2‐LT group) (Odds ratio [OR] 0.676, 95% confidence interval [CI] 0.071–6.426, P = 0.734), but the overall clearance rate of all genital warts was slightly lower for PDT (OR 0.574, CI 0.335–0.985, P = 0.044). The recurrence rate after PDT was significantly lower than after CO2‐LT (OR 0.318, CI 0.220–0.460, P < 0.001), and adverse effects were also slighter after PDT (OR 0.015, CI 0.003–0.074, P < 0.001). In addition, a modification of parameters of light irradiation provides the potential to alleviate pain. This study shows that PDT is an effective treatment for genital warts with good tolerability and safety, especially for cavitary lesions. Some modified protocols probably have the potential to reduce adverse effects, but still need further investigation.

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Photodynamic therapy for intergluteal warts in a child affected by Rett syndrome

Pomi

Macca

Peterle

et al. 2023

Photodiagnosis and Photodynamic Therapy

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HPV condylomatosis region treated with multiple sessions of MAL-PDT: A case report

Cited by 4 publications

References 5 publications

Photodynamic inactivation ofStreptococcus pneumoniaewith external illumination at 808 nm through the ex vivo porcine thoracic cage

Photodynamic inactivation ofStreptococcus pneumoniaewith external illumination at 808 nm through the ex vivo porcine thoracic cage

Topical photodynamic therapy for genital warts: Systematic review and meta‐analysis

Photodynamic therapy for intergluteal warts in a child affected by Rett syndrome

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