Hsa_circ_0002980 prevents proliferation, migration, invasion, and epithelial-mesenchymal transition of liver cancer cells through microRNA-1303/cell adhesion molecule 2 axis
Abstract:Background: Liver cancer (LC) is a hackneyed malignant tumor. And the dysregulation of circular RNA (circRNA) is relevant to the metastasis of LC. Hsa_circ_0002980 was unexpectedly found to be up-regulated in LC tissues, while its specific function remains unclear. Methods: Hsa_circ_0002980 expression was first confirmed by RT-qPCR. Then the impacts of circ_0002980 on the proliferation, metastasis, and EMT-related proteins of LC cells through clone formation, Flow cytometer, Transwell, and western blot. Beside… Show more
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