Hubungan Konsumsi Purin Tinggi Dengan Hiperurisemia: Suatu Penelitian Potong Lintang Pada Penduduk Suku Bali di Kota Denpasar

Indrawan, Ignm Budiana; Kambayana, Gede; Putra, Tjokorda Raka

doi:10.36216/jpd.v1i2.20

Cited by 5 publications

(7 citation statements)

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“…Prevalence of hyperuricemia in the study was higher in comparison to studies from other countries such as US (21.4%), China (8.4%), Northeast China (10.85%), Thailand (10.46%).2, [14][15][16] In comparison to other big cities (Depok and Denpasar; 18.6% and 18.2%. respectively) in Indonesia, prevalence of hyperuricemia in this rural area was also higher.3, 4 Genetic might influence hyperuricemia prevalence in this study. A study in Northern Sulawesi, Indonesia presented that genetic is considered as one of prominent risk factors (OR 14.42 (8.01-26.23) p < 0.0001).…”

Section: Discussionsupporting

confidence: 45%

“…In Depok City, West Java, prevalence of hyperuricemia was 18.6%, while in Denpasar, Bali the prevalence was 18.2%. 3,4 Balance between uric acid production and renal excretion determines the level of serum uric acid. Multiple factors such as race or inheritance, gender, age, obesity, hormones, dietary changes including greater of purine-rich processed foods, alcohol, fructose, lifestyles, and increasing use of diuretics affect serum uric acid level and eventually prevalence of hyperuricemia.…”

Section: Introductionmentioning

confidence: 99%

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Hyperuricemia Prevalence and Its Metabolic Syndrome Profiles

Usman¹,

Darmawan

Hamijoyo

et al. 2019

Ina J Rheum

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Background: The prevalence of hyperuricemia has increased overtime globally. Moreover, it has been linked with several metabolic syndromes. A study in Depok City and Denpasar showed prevalence of hyperuricemia were up to 18.6% and 18.2%, respectively. Urban lifestyle has been proposed to contribute for hyperuricemia; however, there is no published study conducted in rural population yet. Therefore, we performed this study to evaluate the prevalence and metabolic syndromes profile of hyperuricemic patients in rural area. Methods: A cross sectional study was conducted at regional government hospital in North Kayong Regency, West Kalimantan. We retrieved all complete internal medicine outpatient data between October and December 2018. All non-pregnant, adult patients newly diagnosed with hyperuricemia or currently taking uric acid lowering drug were included in this study. Result: A total of 44 out of 121 subjects (36.36%) had hyperuricemia; 25 subjects (56.81%) were male and had median age of 53 years old. Mean level of serum uric acid was 8.30±1.77mg/dl. The metabolic syndrome profiles (diabetes mellitus, obesity, hypertension, hypercholesterolemia and hypertriglyceridemia) vary among subjects; ranging from 20.45% (hypertriglyceridemia) to 86.36% (hypertension). Conclusion: Hyperuricemia and its metabolic disorders are an emerging burden of disease in rural area in Indonesia.

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Section: Discussionsupporting

confidence: 45%

Section: Introductionmentioning

confidence: 99%

Hyperuricemia Prevalence and Its Metabolic Syndrome Profiles

Usman¹,

Darmawan

Hamijoyo

et al. 2019

Ina J Rheum

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“…Penelitian yang dilakukan di kota Denpasar, Bali mendapatkan prevalensi hiperurisemia sebesar 18,2%. (5) Hiperurisemia ini dapat menyebabkan inflamasi vaskuler, proliferasi otot polos, peningkatan produksi renin, dan lesi vaskuler pada ginjal. Lebih jauh lagi hiperurisemia akan menyebabkan perubahan mikrovaskuler pada ginjal yang mirip dengan gambaran arteriosklerosis pada hipertensi esensial.…”

Section: Hiperurisemiaunclassified

Peran Air Rebusan Daun Salam (Syzgium Polyanthum) Dalam Menurunkan Kadar Asam Urat

Darussalam

Rukmi

2019

Media ilmu kesehat.

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Background: Uric acid is a final product or a waste that is resulted from the metabolism of purines. A high level of uric acid (hyperuricemia) will cause several health problems, such as vascular inflammation, smooth muscle proliferation, and vascular lesion in kidneys. The syzygium polyanthum leaves contain bioactive substances that may affect the level of uric acid in blood. Objective: This study aimed to determine the influence of boiled water of syzygium polyanthum leaves to the changes of uric acid levels in the target area of Puskesmas Pandak 1 Bantul. Methods: This study employed pre- and post-test without control group design. The population consisted of all patients with hyperuricemia in the target area of Puskesmas Pandak 1 Bantul. Sample was selected with a concecutive sampling, gaining a total number of 24 respondents. Data were analyzed with the Wilcoxon test. The dose of boiled water of syzygium polyanthum leaves intake was 0.36g/ KgBW, once a day for 14 days. Result: This research showed that the boiled water of syzygium polyanthum leaves decreased hyperuricemia (uric acid levels), along with the significancy value of 0.009 (p <0.05). At the pre-test time, the average level of uric acid reached 7.279 mg/dl, and after the treatment, it decreased to 6.76 mg/dl. Conclusion: This study has established evidence that the boiled water of syzygium polyanthum leaves is able to decrease hyperuricemia (uric acid level in blood). Keywords: Syzygium polyanthum, boiled water of syzygium polyanthum leaves, hyperuricemia

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“…[7] Food consumption patterns of Balinese people are generally in the form of processed foods containing high purines such as pork lawar, chicken betutu, chicken or pork steam, pork satay and grill pork which have the potential to increase uric acid levels and lead to hyperuricemia. [8] The study by Indrawan (2005) found the prevalence of hyperuricemia in Denpasar City at 18.2%. [9] Another study conducted by Diana (2007) found the prevalence of hyperuricemia in the Nusa Ceningan community at 17% .…”

Section: Introductionmentioning

confidence: 99%

“…[8] The study by Indrawan (2005) found the prevalence of hyperuricemia in Denpasar City at 18.2%. [9] Another study conducted by Diana (2007) found the prevalence of hyperuricemia in the Nusa Ceningan community at 17% . [10] Studies on the relationship between intake of purine and blood uric acid levels have been carried out in Bali, but as far as the researchers know, similar studies with postmenopausal female respondents have never been conducted in Denpasar City.…”

Section: Introductionmentioning

confidence: 99%