Huffing and twist: Fatal Torsade de pointes associated with Tetrafluoroethane Inhalation and amphetamine use

Burke, James; Haigney, Mark; Farasat, Morteza; Mehler, Philip S.; Krantz, Mori J.

doi:10.1002/ccr3.3838

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2022

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“…Initial laboratory tests revealed a high sensitivity troponin I level of 2406 ng/l and elevated serum lactate of 6.3 mmol/l. An EKG revealed a rate-corrected QT interval (QTc) of 517 ms with multifocal ventricular ectopy [ 4 ] . This patient had also demonstrated troponemia secondary to inhalant abuse, but it was more significant than in our patient in the setting of post-cardiac arrest myocardial injury.…”

Section: Discussionmentioning

confidence: 99%

Troponemia Secondary to Air Duster Inhalant Abuse

Romero

Abboud

Elkattawy

et al. 2022

European Journal of Case Reports in Internal Medicine

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The abuse of inhalants has become a public health concern in the USA over the past decade. Compressed air duster cans currently available in the USA contain highly toxic substances including different hydrofluorocarbons (including tetrafluoroethane and difluoroethane) which exert a psychoactive effect on the central nervous system. Several cases of inhalant-induced lethal arrhythmia such as ventricular fibrillation evolving to torsade de pointes and leading to cardiac arrest, have been reported in the literature. Furthermore, multiorgan failure including liver and kidney injury has been described after inhalant abuse. We report the case of a 33-year-old man found diaphoretic and with a near syncopal episode after inhalation of several cans of Surf Onn electronic duster gas cleaner, who subsequently developed acute cardiac, liver and kidney injury.

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Section: Discussionmentioning

confidence: 99%