Huge alveolar soft part sarcoma of the retroperitoneum –

Abstract

Alveolar soft part sarcoma (ASPS) is a rare type of neoplasm, typically occurring in adolescents and young adults. Because of the rarity of this disease, there is no standard treatment plan. Chemotherapy and radiotherapy are not effective in this type of malignancy. Surgical excision is considered to be the treatment of choice. We report a case of a young woman with a painless mass in her left lower abdomen. Ultrasonography and CT scan revealed a large (21 cm) hard tumor occupying the left retroperitoneal space, which was surgically excised in our surgery department. The pathological diagnosis was ASPS.

Alveolar soft-part sarcoma of the mediastinum: A case report

“…Notably, in the recent studies, a use of antiangiogenic agents, such as bevacizumab and tyrosine kinase inhibitors, such as sunitinib, reported as treatment for metastatic ASPS. 5–8 Stacchiotti et al 7 reported nine patients with progressive metastatic ASPS who received oral administration of sunitinib 37.5 mg/day. The results were partial response in five cases, stable disease in three, and progression in one.…”

Leiomyosarcoma in adrenal gland

“…The diagnostic process of sarcomas located in the retroperitoneum is challenging due to its asymptomatic clinical picture, which was observed in other types of neoplasms as well [3]. Gradual growth of leiomyosarcoma will eventually apply pressure to adjacent structures, provoking abdominal pain, which might manifest as several other diseases.…”