Huge myxoid chondrosarcoma expanded into the thoracic cavity with spinal involvement

Lu, Ming; Zhou, Zhongxin; Lei, Zixiong; Li, Haomiao; Boriani, Stefano

doi:10.1007/s00586-018-5689-7

Cited by 2 publications

(3 citation statements)

References 32 publications

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“…Similarly, a systematic review reported that the negative margin rate obtained following en bloc resection of 229 primary spinal tumors was 86.1% ( 25 ), and a study from a single center of 220 spinal tumors that underwent en bloc resection found that the negative margin rate was 85.9% ( 23 ). Careful planning and efficient design of surgical procedures can be successful in obtaining oncologically appropriate margins, even in difficult cases ( 9 ).…”

Section: Discussionmentioning

confidence: 99%

“…Obstacles to en bloc resection of spinal tumors include regional anatomical limitations and large tumor volumes (6)(7)(8). Due to the lack of surrounding anatomical barriers over the surface of the vertebral body, bone tumors that break through the cortical bone and longitudinal ligament can easily grow into huge masses outside the spinal column (9). Factors associated with large tumor sizes include the long duration of symptoms before seeking medical care (sometimes from months to years) and recurrence after non-standard operations (e.g., curettage or intralesional resection).…”

Section: Introductionmentioning

confidence: 99%

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En bloc resection of huge primary tumors with epidural involvement in the mobile spine using the “rotation–reversion” technique: Feasibility, safety, and clinical outcome of 11 cases

Zhou

Chen

et al. 2022

Front. Oncol.

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BackgroundEn bloc resection of spinal tumors provides better local control and survival outcomes than intralesional resection. Safe margins during en bloc resection of primary spinal tumors with epidural involvement are required for improved outcomes. The present study describes a “rotation–reversion” technique that has been used for en bloc resection of huge primary tumors in the mobile spine with epidural involvement and reported the clinical outcomes in these patients.MethodsAll patients with primary spinal tumors who were treated with the rotation–reversion technique at our institution between 2015 and 2021 were evaluated retrospectively. Of the patients identified, those with both huge extraosseous soft-tissue masses and epidural involvement were selected for a case review. Clinical and radiological characteristics, pathologic findings, operative procedures, complications, and oncological and functional outcomes of these patients were reviewed.ResultsOf the 86 patients identified with primary spinal tumors who underwent en bloc resection using the rotation–reversion technique between 2015 and 2021, 11 had huge extraosseous soft-tissue masses with epidural involvement in the mobile spine. The average maximum size of these 11 tumors was 8.1 × 7.5 × 9.7 cm. Median follow-up time was 28.1 months, mean operation time was 849.1 min (range 465–1,340 min), and mean blood loss was 6,972.7 ml (range 2,500–17,700 ml), with 10 (91%) of the 11 patients experiencing perioperative complications. The negative margin rate was 91%, with only one patient (9%) experiencing local recurrence. Ten patients were able to walk normally or with a crutch at the last follow-up, whereas one was completely paralyzed preoperatively.ConclusionThe rotation–reversion technique is an effective procedure for the en bloc resection of huge primary spinal tumors, with the extension of invasion in selected patients including not only the vertebral body but also the pedicle and part of the posterior arch.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

En bloc resection of huge primary tumors with epidural involvement in the mobile spine using the “rotation–reversion” technique: Feasibility, safety, and clinical outcome of 11 cases

Zhou

Chen

et al. 2022

Front. Oncol.

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“…A giant thoracic tumor is a kind of rare tumor clinically [1][2][3]. Because of its complicated pathological types and prognosis, there is no unified standard for the diagnosis and treatment, and surgical resection becomes the major clinical treatment means [4][5][6][7].…”

Section: Introductionmentioning

confidence: 99%

Impact Evaluation of Comfort Care on the Prognosis of Giant Thoracic Tumor Patients with Computerized Tomography Imaging under Intelligent Reconstruction Algorithm

Yan

2022

Scientific Programming

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The reconstruction algorithm based on the network of generative adversarial and contextual coding (RANGC) was proposed in this study to analyze the impacts on the prognosis of patients with giant thoracic tumors with CT imaging under artificial intelligence algorithms. The algorithms of Feldkamp–Davis–Kress (FDK) and the generative adversarial network (GAN) were introduced. The patients were divided into the test group with comfort care and the control group with conventional care. Three sets of indicators below were also compared between the patients in two groups, including the pain level and complication incidence, the self-rating anxiety scale (SAS), the self-rating depression scale (SDS), and the patients’ satisfaction and average duration of hospital stay. When the scanning range was [0°, 89°], the peak signal-to-noise ratio (PSNR) and structural similarity index measurement (SSIM) under the RANGC algorithm were 45.6 dB and 0.99, respectively. When the scanning range changed to [0°, 119°], the PSNR and SSIM were 39.21 dB and 0.98, respectively. The results were significantly higher than those under the FDK and GAN algorithms, and the difference was obviously of statistical significance P < 0.05 . The average postoperative pain level of the patients in the control group was 3.12 points, and the postoperative complication incidence was 36.13%, while those of the test group patients were 2.27 points and 20.02%, respectively, which was greatly lower than those of the control group patients, and such a difference was of statistical significance P < 0.05 . There was no statistically significant difference in the SDS and SAS scores between the patients in the two groups before surgery. However, the SAS and SDS scores of the test group patients were 41.23 and 43.25, respectively, after surgery, which are obviously lower than those of the control group patients, with a statistically significant difference P < 0.05 . The average duration of hospital stay of the test group patients was 6.31 days, which was lower than that of the control group patients, with a statistically significant difference P < 0.05 . The overall satisfaction of the test group patients was 83.33%, which was remarkably higher than that of the control group patients, and the difference had statistical significance P < 0.05 . All these showed that the performance of the RANGC algorithm was relatively better, and comfort care did good to improve the negative mood, satisfaction, and life quality of patients after surgery.

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Huge myxoid chondrosarcoma expanded into the thoracic cavity with spinal involvement

Abstract: A careful planning and a multidisciplinary collaboration make possible to perform en bloc resection even in apparently impossible cases.

Cited by 2 publications

References 32 publications

En bloc resection of huge primary tumors with epidural involvement in the mobile spine using the “rotation–reversion” technique: Feasibility, safety, and clinical outcome of 11 cases

En bloc resection of huge primary tumors with epidural involvement in the mobile spine using the “rotation–reversion” technique: Feasibility, safety, and clinical outcome of 11 cases

Impact Evaluation of Comfort Care on the Prognosis of Giant Thoracic Tumor Patients with Computerized Tomography Imaging under Intelligent Reconstruction Algorithm

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