Huge Pyogenic Granuloma of the Penis

Abstract

Pyogenic granulomas are benign vascular disorders of the skin and mucose membranes, generally developed by trauma and irritation. The lesions are generally small. They are most commonly seen in the skin and oral mucosa and rarely seen on penis. We present the case of a huge pyogenic granuloma on the penis.

Vulvar Lobular Capillary Hemangioma: A Rare Location for a Frequent Entity

“…The etiology of this disease is not yet fully understood. It has been considered to be a reactive hyperproliferative vascular response to a variety of stimuli, more than a true hemangioma [1, 3, 4]. Recently, the likely explanation for the pathogenesis is an excessive local production of tumor angiogenesis factor, as a result of minor trauma or an underlying cutaneous disease [4].…”

“…There are various treatment options for PG: surgical excision, cryotherapy, sclerotherapy, curettage followed by electrocauterization, lasers, 5% imiquimod cream, and microembolization [2, 3]. Recently, there were reports of the use of a new topical treatment option, timolol, apparently with minimal adverse effects, easy administration, and good cosmetic outcomes [11, 12].…”

“…Besides that, it has some additional advantages, considering it is a single step treatment and the lesion can be sent to pathological evaluation [4]. Cryotherapy also has a low recurrence risk and, among the nonsurgical treatment options, is a good choice to sensitive areas like the face and neck [2, 3]. …”

“…Lobular capillary hemangioma or pyogenic granuloma, as it is usually known, is an acquired hemorrhagic benign vascular lesion of the skin and mucous membranes [1–3]. This hypervascularized lesion grows rapidly (in weeks or months) and usually presents as pedunculated or sessile mass, friable polypoid, and exophytic lesion, with a smooth or lobulated surface [1–4].…”

Giant pyogenic granuloma on the glans penis

“…The etio-pathogenesis of PG is largely unknown. It is considered to be a reactive phenomenon in which trauma, irritation or other unknown stimuli leads to angiogenesis and vascular proliferation [ 2 ]. Histopathological examination usually reveals lobules of small capillaries in a fibro-myxoid matrix with thinned out epidermis [ 2 ].…”