Human albumin from cord blood: Some distinctive characteristics

Gallango, María de L.; Montiel, Nola; Suinaga, R.

doi:10.1016/0006-2944(81)90038-7

Cited by 3 publications

(1 citation statement)

References 10 publications

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“…Albumin is a major binding protein found in human neonates. The fatal albumin has an anodic electrophoretic migration at pH 5.3 and a greater affinity to bind the bromocresol green dye [18]. By competing with tissue for bilirubin binding, albumin decreases bilirubin toxicity.…”

Section: Introductionmentioning

confidence: 99%

Development of Non-Invasive Biosensors for Neonatal Jaundice Detection: A Review

Hazarika,

Borah,

Gogoi

et al. 2024

Biosensors

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One of the most common problems many babies encounter is neonatal jaundice. The symptoms are yellowing of the skin or eyes because of bilirubin (from above 2.0 to 2.5 mg/dL in the blood). If left untreated, it can lead to serious neurological complications. Traditionally, jaundice detection has relied on invasive blood tests, but developing non-invasive biosensors has provided an alternative approach. This systematic review aims to assess the advancement of these biosensors. This review discusses the many known invasive and non-invasive diagnostic modalities for detecting neonatal jaundice and their limitations. It also notes that the recent research and development on non-invasive biosensors for neonatal jaundice diagnosis is still in its early stages, with the majority of investigations being in vitro or at the pre-clinical level. Non-invasive biosensors could revolutionize neonatal jaundice detection; however, a number of issues still need to be solved before this can happen. These consist of in-depth validation studies, affordable and user-friendly gadgets, and regulatory authority approval. To create biosensors that meet regulatory requirements, additional research is required to make them more precise and affordable.

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Section: Introductionmentioning

confidence: 99%

Development of Non-Invasive Biosensors for Neonatal Jaundice Detection: A Review

Hazarika,

Borah,

Gogoi

et al. 2024

Biosensors

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Plasma protein binding of ritodrine at parturition and in nonpregnant women

Gross

Brown

1985

Eur J Clin Pharmacol

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The binding of ritodrine HCl in whole plasma from healthy nonpregnant women, parturients and matched umbilical venous plasma and in solutions of HSA and alpha 1-AGP has been studied by equilibrium dialysis. Binding to plasma from nonpregnant subjects and HSA was independent of ritodrine concentration over a wide range. The free fraction in plasma was high and significantly different between groups of nonpregnant (alpha = 0.64), parturient (alpha = 0.68) and matched umbilical venous plasma (alpha = 0.75). It would seem that variability in transplacental transfer of ritodrine, as a result of plasma binding fluctuations, will be minor.

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1995

All About Albumin

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Human albumin from cord blood: Some distinctive characteristics

Cited by 3 publications

References 10 publications

Development of Non-Invasive Biosensors for Neonatal Jaundice Detection: A Review

Development of Non-Invasive Biosensors for Neonatal Jaundice Detection: A Review

Plasma protein binding of ritodrine at parturition and in nonpregnant women

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