Human Brucellosis: Are we neglecting an enemy at the backyard?

Pandit, D; Pandit, Padmakar

doi:10.4103/0975-2870.118265

Cited by 17 publications

(17 citation statements)

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“…More than 60% of emerging human pathogens are zoonotic [1] and brucellosis is the most widespread zoonosis in the world caused by bacteria belonging to genus Brucella [2][3][4][5]. Among the recognized 12 Brucella species, Brucella melitensis, Brucella suis and Brucella abortus are the major human pathogens resulting in considerable disability and morbidity [6,7].…”

Section: Introductionmentioning

confidence: 99%

Prevalence and risk factors of brucellosis among veterinary health care professionals

Shome

Kalleshamurthy

Shankaranarayana

et al. 2017

Pathogens and Global Health

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The study describes prevalence, clinical symptoms and risk factors for brucellosis in personnel engaged in veterinary health care in Karnataka, India. A total of 1050 sera samples were collected from animal handlers, veterinarians, veterinary students, para-veterinarians and persons engaged in artificial insemination of animals. The sera samples were tested for brucellosis by Rose Bengal plate test (RBPT), serum agglutination test (SAT), IgG and IgM indirect ELISA and PCR. Age, sex, clinical symptoms and risk factors were recorded in structured questionnaire. Of the 1050 samples tested, 6.76, 6.38, 3.90, 2.67 and 2.0% were positive by IgG ELISA, RBPT, SAT, IgM ELISA and PCR, respectively and overall prevalence recorded was 7.04%. The prominent clinical symptoms observed were intermittent fever (71.62%) followed by joint pain and body aches. A high degree of suspicion, awareness and multimodal diagnostic approach is suggested for early diagnosis, treatment and disease follow up.

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Section: Introductionmentioning

confidence: 99%

Prevalence and risk factors of brucellosis among veterinary health care professionals

Shome

Kalleshamurthy

Shankaranarayana

et al. 2017

Pathogens and Global Health

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“…Lack of awareness among clinicians, low index of suspicion and non-availability of diagnostic tests can all lead to missed diagnosis of brucellosis [259]. The disease is easily treatable and can be completely cured but failure to diagnose brucellosis early may lead to delayed institution of appropriate antimicrobial therapy and this increases the chances of treatment failure [259]. Having a high index of suspicion, prompt diagnosis and appropriate as well as adequate treatment can cure the patient, prevent chronic morbidity and prevent loss of valuable time to treatment of the infection at an early stage [259].…”

Section: Treatment Of Brucellosismentioning

confidence: 99%

Brucellosis in Immunocompromised Hosts

Ka¹,

Al-Jasser²

2016

Arch Organ Transplant

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Archives of Organ Transplantation eertechz 001 and treatment may be delayed [4]. Therefore, sustaining a high index of suspicion is important as early diagnosis and prompt therapy improve the outcome and prevent complications [1,3,4]. This review on Brucella infections in immunocompromised individuals, will be an update on the following aspects of brucellosis: (1) epidemiology, pathogenesis, microbiology, clinical manifestations and complications, (2) Brucella infections in various categories of immunocompromised individuals, and (3) diagnostic techniques, available therapies, prevention and control of the infection. However, particular attention will be given to brucellosis in recipients of stem cell and solid organ transplantation. Incidence and epidemiology Brucellosis is an infectious disease of animals (zoonosis) that is transmittable to humans by wild and domestic animals [5]. Several Brucella species have been identified, 6 of which are human pathogens [5-8]. The incidence of brucellosis varies considerably from time to time and from one country to another [9,10]. Several studies have shown that the annual incidence of brucellosis per million of population is as follows: 0.

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“…Brucellosis is caused by members of bacterial genus Brucella which is a facultative intracellular Gram-negative pathogen. Brucellosis is a common but neglected disease in India[ 1 ] and can be treated with antibiotic but is often misdiagnosed because of the difficult diagnosis and lack of experience with laboratory testing. Although North Karnataka is endemic for brucellosis, case reports are predominantly from Belgaum and Bijapur district.…”

Section: Introductionmentioning

confidence: 99%

Triad of infective endocarditis, splenic abscess, and septicemia caused by Brucella melitensis

et al. 2017

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A 40-year-old farmer from the district of North Karnataka who had received treatment for high fever of 8 days duration was admitted with fever, dyspnea, and poor general condition. Ultrasonography and echocardiogram revealed multiple splenic abscesses, vegetation on atrioventricular valve, aortic regurgitation (Grade I–II), and mitral valve regurgitation (Grade II–III), respectively. Brucella melitensis was detected in blood culture, and high titers of IgM and IgG anti-Brucella antibodies were observed in Brucella specific serological tests. The patient developed fulminant septicemia and succumbed due to multi-organ failure.

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Human Brucellosis: Are we neglecting an enemy at the backyard?

Cited by 17 publications

References 0 publications

Prevalence and risk factors of brucellosis among veterinary health care professionals

Prevalence and risk factors of brucellosis among veterinary health care professionals

Brucellosis in Immunocompromised Hosts

Triad of infective endocarditis, splenic abscess, and septicemia caused by Brucella melitensis

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