Human Cases of Fascioliasis in Fujian Province, China

Ai, Lin; Cai, Yangchuan; Lu, Yan; Chen, Jiaxu; Chen, Shaohong

doi:10.3347/kjp.2017.55.1.55

Cited by 10 publications

(4 citation statements)

References 28 publications

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“…In this study, no change in the value of AFP and CEA was observed for all the rabbit sera. Our data are in agreement with previous case reports indicating that tumor markers including AFP and CEA were at normal value in human fascioliasis [ 1 , 14 , 15 , 28 ]. This suggested that there might be no relationship between fascioliasis and cholangiocarcinoma, at least at the acute phase.…”

supporting

confidence: 93%

Dynamics of liver enzymes in rabbits experimentally infected with <i>Fasciola</i> sp. (Intermediate form from Japan)

Jarujareet

Taira

Ooi

2018

The Journal of Veterinary Medical Science

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Dynamics of serum liver enzymes in rabbits experimentally infected with metacercariae of Fasciola sp. (intermediate form between Fasciola hepatica and F. gigantica) were monitored. Gradual increase of serum aspartate aminotransferase (AST) and alanine aminotransferase (ALT) were observed from 3 weeks post-inoculation (WPI) and peaked at 6 WPI, which corresponded well to the period of migration and development of juvenile fluke in the liver parenchyma and the time when the young adult flukes migrated to the bile duct. However, no significant increase in serum gamma-glutamyl transferase (GGT) and alkaline phosphatase (ALP) were observed. This could reflect reduced or minimal injury of bile ducts and biliary epithelia as the flukes had reached the adult stage. Alpha-fetoprotein (AFP) and carcinoembryonic antigen (CEA) were not detected in the infected rabbit during the course of the experiment. Serum liver enzymes monitoring might be useful for understanding the host-parasite relationship in fascioliasis.

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supporting

confidence: 93%

Dynamics of liver enzymes in rabbits experimentally infected with <i>Fasciola</i> sp. (Intermediate form from Japan)

Jarujareet

Taira

Ooi

2018

The Journal of Veterinary Medical Science

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“…A prevalence of 0.011% was reported in the national survey conducted in 1988–1992, with cases found in eight provinces [56], while it decreased to 0.0007% in the national survey done in 2014–2015 [51]. Although the overall prevalence is very low, several outbreaks have been reported recently [55, 57]. The low awareness of this infection in the public usually leads to severe delays in the diagnosis and subsequent management of the disease.…”

Section: Progress In the Control And Elimination Of Ntds In The Peoplmentioning

confidence: 99%

Neglected tropical diseases in the People’s Republic of China: progress towards elimination

Qian

Chen

Bergquist³

et al. 2019

Infect Dis Poverty

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Since the founding of the People's Republic of China in 1949, considerable progress has been made in the control and elimination of the country's initial set of 11 neglected tropical diseases. Indeed, elimination as a public health problem has been declared for lymphatic filariasis in 2007 and for trachoma in 2015. The remaining numbers of people affected by soil-transmitted helminth infection, clonorchiasis, taeniasis, and echinococcosis in 2015 were 29.1 million, 6.0 million, 366 200, and 166 100, respectively. In 2017, after more than 60 years of uninterrupted, multifaceted schistosomiasis control, has seen the number of cases dwindling from more than 10 million to 37 600. Meanwhile, about 6000 dengue cases are reported, while the incidence of leishmaniasis, leprosy, and rabies are down at 600 or fewer per year. Sustained social and economic development, going hand-in-hand with improvement of water, sanitation, and hygiene provide the foundation for continued progress, while rigorous surveillance and specific public health responses will consolidate achievements and shape the elimination agenda. Targets for poverty elimination and strategic plans and intervention packages post-2020 are important opportunities for further control and elimination, when remaining challenges call for sustainable efforts.

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“…The infection may also be acquired through consumption of water contaminated by encysted metacercaria, or food items washed with such water (Ibrahim 2017 ) or consumption of contaminated water of human sewage (Aleixo et al 2015 ). According to the World Health Organization (WHO), human fasciolosis is classified as a Neglected Tropical Disease (NTD) (Ai et al 2017 ; Abah et al 2019 ). Human fasciolosis is a major public health problem in several areas of the world, with human cases being increasingly reported from Europe, the Americas, Oceania, India and Africa (Aksoy et al 2005 ; Soliman 2008 ).…”

Section: Introductionmentioning

confidence: 99%

Prevalence and associated risk factors assessment of bovine fasciolosis in the Imbo Region, Burundi

Nkurunziza,

Nishemezwe,

Ntirandekura

et al. 2023

Parasitol Res

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Fasciolosis is a zoonosis that limits the productivity of ruminants worldwide, but there is a lack of information on its occurrence in Burundi. Therefore, this study aimed to fill the information gap by determining the prevalence and risk factors associated with bovine fasciolosis in the Imbo Region of Burundi. Two prevalence studies were conducted in parallel in the five communes of the five provinces in the Imbo region. In the first study, a total of 426 fecal samples were collected from randomly selected cattle farms and microscopically examined to determine Fasciola egg burden. Survey data on cattle husbandry were collected from owners of these cattle and analyzed to determine the risk factors for bovine fasciolosis. In the second study, 467 cattle were randomly selected in abattoirs and their livers were examined postmortem to determine liver fluke burdens. Data were entered separately into Microsoft Excel and analyzed using R software. The overall prevalence of bovine fasciolosis was 47.7% (42.9–52.4, 95% CI) for microscopic examination and 33.2% (28.9–37.5, 95% CI) for postmortem examinations. The majority of positive cattle (60.6%) had light intensity infections as determined by eggs per gram of feces (epg). Postmortem examinations corroborated these results and indicated that 80% of cattle had light intensity infections. Chi-square analysis showed a statistical association with the presence of bovine fasciolosis and the age, sex, and origin of cattle and the practices of cattle owners (P < 0.05).

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Human Cases of Fascioliasis in Fujian Province, China

Cited by 10 publications

References 28 publications

Dynamics of liver enzymes in rabbits experimentally infected with <i>Fasciola</i> sp. (Intermediate form from Japan)

Dynamics of liver enzymes in rabbits experimentally infected with <i>Fasciola</i> sp. (Intermediate form from Japan)

Neglected tropical diseases in the People’s Republic of China: progress towards elimination

Prevalence and associated risk factors assessment of bovine fasciolosis in the Imbo Region, Burundi

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